[PDF][PDF] Parallel processing of two mechanosensory modalities by a single neuron in C. elegans

L Tao, D Porto, Z Li, S Fechner, SA Lee, MB Goodman… - Developmental cell, 2019 - cell.com
Neurons convert synaptic or sensory inputs into cellular outputs. It is not well understood
how a single neuron senses, processes multiple stimuli, and generates distinct neuronal …

Graphical-model framework for automated annotation of cell identities in dense cellular images

S Chaudhary, SA Lee, Y Li, DS Patel, H Lu - Elife, 2021 - elifesciences.org
Although identifying cell names in dense image stacks is critical in analyzing functional
whole-brain data enabling comparison across experiments, unbiased identification is very difficult…

Multi‐level micro/nanotexturing by three‐dimensionally controlled photofluidization and its use in plasmonic applications

HS Kang, S Lee, SA Lee, JK Park - Advanced Materials, 2013 - Wiley Online Library
Micro/nanotextured surfaces have been utilized to induce many important natural and artificial
phenomena: examples include the superhydrophobicity at the surface of a lotus leaf,[1, 2] …

[HTML][HTML] On-chip functional neuroimaging with mechanical stimulation in Caenorhabditis elegans larvae for studying development and neural circuits

Y Cho, DN Oakland, SA Lee, WR Schafer, H Lu - Lab on a Chip, 2018 - pubs.rsc.org
Mechanosensation is fundamentally important for the abilities of an organism to experience
touch, hear sounds, and maintain balance. Caenorhabditis elegans is a powerful system for …

Vertically oriented, three-dimensionally tapered deep-subwavelength metallic nanohole arrays developed by photofluidization lithography.

SA Lee, HS Kang, JK Park, S Lee - Advanced Materials (Deerfield …, 2014 - europepmc.org
The field-gradient, superficial photo fluidization of azomaterials allows a specific 3D nano-silhouette
to be shaped over a large area, so as to get easy access to a 3D-tapered, deep sub-…

[PDF][PDF] Ankyrin is an intracellular tether for TMC mechanotransduction channels

YQ Tang, SA Lee, M Rahman, SA Vanapalli, H Lu… - Neuron, 2020 - cell.com
Mechanotransduction channels have been proposed as force sensors in various physiological
processes, such as hearing and touch. In particular, TMC1 has been shown to constitute …

Editor's highlight: a genome-wide screening of target genes against silver nanoparticles in fission yeast

AR Lee, SJ Lee, M Lee, M Nam, S Lee… - Toxicological …, 2018 - academic.oup.com
To identify target genes against silver nanoparticles (AgNPs), we screened a genome-wide
gene deletion library of 4843 fission yeast heterozygous mutants covering 96% of all protein …

Multimodal Stimulation in a Microfluidic Device Facilitates Studies of Interneurons in Sensory Integration in C. elegans

Y Cho, SA Lee, YL Chew, K Broderick, WR Schafer… - Small, 2020 - Wiley Online Library
Animals' perception and behavior involve integration of multiple sensory modalities. Caenorhabditis
elegans is a useful model for studying multimodal sensory integration, as it has well‐…

Thalamic degeneration in MPTP-treated Parkinsonian monkeys: impact upon glutamatergic innervation of striatal cholinergic interneurons

RM Villalba, JF Pare, S Lee, S Lee, Y Smith - Brain Structure and Function, 2019 - Springer
In both Parkinson’s disease (PD) patients and MPTP-treated non-human primates, there is
a profound neuronal degeneration of the intralaminar centromedian/parafascicular (CM/Pf) …

[HTML][HTML] The PI3Kδ inhibitor idelalisib inhibits homing in an in vitro and in vivo model of B ALL

E Adam, HN Kim, EJ Gang, C Schnair, S Lee, S Lee… - Cancers, 2017 - mdpi.com
The quest continues for targeted therapies to reduce the morbidity of chemotherapy and to
improve the response of resistant leukemia. Adhesion of acute lymphoblastic leukemia (ALL) …