[HTML][HTML] Digital health: tracking physiomes and activity using wearable biosensors reveals useful health-related information

…, E Colbert, R Runge, S Rego, R Sonecha, S Datta… - PLoS …, 2017 - journals.plos.org
A new wave of portable biosensors allows frequent measurement of health-related physiology.
We investigated the use of these devices to monitor human physiological changes during …

A new paradigm for accelerating clinical data science at Stanford Medicine

S Datta, J Posada, G Olson, W Li, C O'Reilly… - arXiv preprint arXiv …, 2020 - arxiv.org
Stanford Medicine is building a new data platform for our academic research community to do
better clinical data science. Hospitals have a large amount of patient data and researchers …

[HTML][HTML] A scalable, secure, and interoperable platform for deep data-driven health management

…, K Contrepois, U Ray, K Bettinger, S Datta… - Nature …, 2021 - nature.com
The large amount of biomedical data derived from wearable sensors, electronic health
records, and molecular profiling (eg, genomics data) is rapidly transforming our healthcare …

The Stanford Medicine data science ecosystem for clinical and translational research

A Callahan, E Ashley, S Datta, P Desai, TA Ferris… - JAMIA …, 2023 - academic.oup.com
Objective To describe the infrastructure, tools, and services developed at Stanford Medicine
to maintain its data science ecosystem and research patient data repository for clinical and …

Gradient clogging in depth filtration

S Datta, S Redner - Physical Review E, 1998 - APS
We investigate clogging in depth filtration, in which a dirty fluid is “cleaned” by the trapping
of dirt particles within the pore space during flow through a porous medium. This leads to a …

Clogging time of a filter

S Redner, S Datta - Physical Review Letters, 2000 - APS
We study the time until a filter becomes clogged due to the trapping of suspended particles
as they pass through a porous medium. This trapping progressively impedes and eventually …

Secure cloud computing for genomic data

S Datta, K Bettinger, M Snyder - Nature biotechnology, 2016 - nature.com
Figure 1 Security stack. High-level features—infrastructure security, data access controls
and security management (dark blue boxes)—that cloud security must meet for genomics …

[HTML][HTML] Benchmarking workflows to assess performance and suitability of germline variant calling pipelines in clinical diagnostic assays

V Krishnan, S Utiramerur, Z Ng, S Datta, MP Snyder… - BMC …, 2021 - Springer
Background Benchmarking the performance of complex analytical pipelines is an essential
part of developing Lab Developed Tests (LDT). Reference samples and benchmark calls …

[HTML][HTML] Sequence to medical phenotypes: a framework for interpretation of human whole genome DNA sequence data

…, C Miyake, M Whirl-Carrillo, TE Klein, S Datta… - PLoS …, 2015 - journals.plos.org
High throughput sequencing has facilitated a precipitous drop in the cost of genomic
sequencing, prompting predictions of a revolution in medicine via genetic personalization of …

High performance on-demand de-identification of a petabyte-scale medical imaging data lake

J Mesterhazy, G Olson, S Datta - arXiv preprint arXiv:2008.01827, 2020 - arxiv.org
With the increase in Artificial Intelligence driven approaches, researchers are requesting
unprecedented volumes of medical imaging data which far exceed the capacity of traditional on-…