Human trophoblast epithelial-mesenchymal transition in abnormally invasive placenta
SC DaSilva-Arnold, S Zamudio, A Al-Khan… - Biology of …, 2018 - academic.oup.com
Differentiation of first trimester human placental cytotrophoblast (CTB) from an anchorage-dependent
epithelial phenotype into the mesenchymal-like invasive extravillous trophoblast (…
epithelial phenotype into the mesenchymal-like invasive extravillous trophoblast (…
Trophoblast invasion: Lessons from abnormally invasive placenta (placenta accreta)
NP Illsley, SC DaSilva-Arnold, S Zamudio, M Alvarez… - Placenta, 2020 - Elsevier
The invasion of the uterine wall by extravillous trophoblast is acknowledged as a crucial
component of the establishment of pregnancy however, the only part of this process that has …
component of the establishment of pregnancy however, the only part of this process that has …
ZEB2, a master regulator of the epithelial–mesenchymal transition, mediates trophoblast differentiation
STUDY QUESTION Does the upregulation of the zinc finger E-box binding homeobox 2 (ZEB2)
transcription factor in human trophoblast cells lead to alterations in gene expression …
transcription factor in human trophoblast cells lead to alterations in gene expression …
[HTML][HTML] Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated …
…, L Maldonado, A Singh, SC DaSilva-Arnold… - Genome biology, 2020 - Springer
Background Mapping of allele-specific DNA methylation (ASM) can be a post-GWAS
strategy for localizing regulatory sequence polymorphisms (rSNPs). The advantages of this …
strategy for localizing regulatory sequence polymorphisms (rSNPs). The advantages of this …
Diminished trophoblast differentiation in early onset preeclampsia
A Natenzon, P McFadden, SC DaSilva-Arnold… - Placenta, 2022 - Elsevier
The mechanism by which human cytotrophoblast cells (CTB) differentiate into extravillous
trophoblast cells (EVT) is an epithelial-mesenchymal transition (EMT). Polarized CTB, …
trophoblast cells (EVT) is an epithelial-mesenchymal transition (EMT). Polarized CTB, …
Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity
…, SR Mehta, DR Mohamed, SC DaSilva-Arnold… - Cancer research, 2013 - AACR
Field cancerization refers to areas of grossly normal epithelium that exhibit increased risk for
tumor occurrence. Unfortunately, elucidation of the locoregional changes that contribute to …
tumor occurrence. Unfortunately, elucidation of the locoregional changes that contribute to …
Topical Application of a Vitamin D Analogue Exacerbates Atopic Dermatitis and Induces the Atopic Dermatitis‐like Phenotype in Stat6 VT Mice
MJ Turner, SC DaSilva‐Arnold, Q Yi… - Pediatric …, 2013 - Wiley Online Library
Calcipotriene is a topical vitamin D 3 analogue approved for the treatment of plaque and scalp
psoriasis. We report the case of a 2‐year‐old boy whose atopic dermatitis ( AD ) flared in …
psoriasis. We report the case of a 2‐year‐old boy whose atopic dermatitis ( AD ) flared in …
Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis
SC DaSilva-Arnold, A Thyagarajan, LJ Seymour… - Archives of …, 2018 - Springer
The Stat6VT mouse model of atopic dermatitis (AD) is induced by T-cell-specific expression
of a constitutively active form of the protein signal transducer and activator of transcription 6 (…
of a constitutively active form of the protein signal transducer and activator of transcription 6 (…
[HTML][HTML] Topical application of a platelet activating factor receptor agonist suppresses phorbol ester-induced acute and chronic inflammation and has cancer …
RP Sahu, S Rezania, JA Ocana, SC DaSilva-Arnold… - PLoS …, 2014 - journals.plos.org
Platelet activating factor (PAF) has long been associated with acute edema and inflammatory
responses. PAF acts by binding to a specific G-protein coupled receptor (PAF-R, Ptafr). …
responses. PAF acts by binding to a specific G-protein coupled receptor (PAF-R, Ptafr). …
IFPA meeting 2016 workshop report III: Decidua-trophoblast interactions; trophoblast implantation and invasion; immunology at the maternal-fetal interface; placental …
…, A Beristain, S DaSilva-Arnold, C Dunk, C Duzyj… - Placenta, 2017 - Elsevier
… Sonia DaSilva-Arnold discussed how there may be a disconnection between EVT genotype
and phenotype in abnormally invasive placenta. There is a need to acknowledge the role of …
and phenotype in abnormally invasive placenta. There is a need to acknowledge the role of …