Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury
ABSTRACT Systems biology offers considerable promise in uncovering novel pathways by
which viruses and other microbial pathogens interact with host signaling and expression …
which viruses and other microbial pathogens interact with host signaling and expression …
[PDF][PDF] Cytomegalovirus miRNAs target secretory pathway genes to facilitate formation of the virion assembly compartment and reduce cytokine secretion
…, R Tirabassi, T Doyle, M Hancock, I Landais, S Jeng… - Cell host & …, 2014 - cell.com
Herpesviruses, including human cytomegalovirus (HCMV), encode multiple microRNAs (miRNA)
whose targets are just being uncovered. Moreover, miRNA function during the virus life …
whose targets are just being uncovered. Moreover, miRNA function during the virus life …
A microRNA screen identifies the Wnt signaling pathway as a regulator of the interferon response during flavivirus infection
JL Smith, S Jeng, SK McWeeney, AJ Hirsch - Journal of virology, 2017 - Am Soc Microbiol
The impact of mosquito-borne flavivirus infections worldwide is significant, and many critical
aspects of these viruses' biology, including virus-host interactions, host cell requirements for …
aspects of these viruses' biology, including virus-host interactions, host cell requirements for …
Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer
Weight loss and anorexia are common symptoms in cancer patients that occur prior to
initiation of cancer therapy. Inflammation in the brain is a driver of these symptoms, yet cellular …
initiation of cancer therapy. Inflammation in the brain is a driver of these symptoms, yet cellular …
[HTML][HTML] Maternal high-fat diet and obesity compromise fetal hematopoiesis
…, X Zhu, QR Roth-Carter, PR Levasseur, S Jeng… - Molecular …, 2015 - Elsevier
Objective Recent evidence indicates that the adult hematopoietic system is susceptible to
diet-induced lineage skewing. It is not known whether the developing hematopoietic system is …
diet-induced lineage skewing. It is not known whether the developing hematopoietic system is …
[PDF][PDF] In vivo repair of a protein underlying a neurological disorder by programmable RNA editing
…, SY Kim, JR Fisk, Z Song, H Nakai, S Jeng… - Cell reports, 2020 - cell.com
Programmable RNA editing is gaining momentum as an approach to repair mutations, but
its efficiency in repairing endogenous mutant RNA in complex tissue is unknown. Here we …
its efficiency in repairing endogenous mutant RNA in complex tissue is unknown. Here we …
REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation–differentiation balance in the developing brain
CE Monaghan, T Nechiporuk, S Jeng… - Proceedings of the …, 2017 - National Acad Sciences
The transcriptional events that lead to the cessation of neural proliferation, and therefore
enable the production of proper numbers of differentiated neurons and glia, are still largely …
enable the production of proper numbers of differentiated neurons and glia, are still largely …
Host regulatory network response to infection with highly pathogenic H5N1 avian influenza virus
C Li, A Bankhead III, AJ Eisfeld, Y Hatta, S Jeng… - Journal of …, 2011 - Am Soc Microbiol
During the last decade, more than half of humans infected with highly pathogenic avian
influenza (HPAI) H5N1 viruses have died, yet virus-induced host signaling has yet to be clearly …
influenza (HPAI) H5N1 viruses have died, yet virus-induced host signaling has yet to be clearly …
Targeted RNA editing in brainstem alleviates respiratory dysfunction in a mouse model of Rett syndrome
…, JF Yung, JR Fisk, S Jeng… - Proceedings of the …, 2022 - National Acad Sciences
Rett syndrome is a neurological disease due to loss-of-function mutations in the transcription
factor, Methyl CpG binding protein 2 (MECP2). Because overexpression of endogenous …
factor, Methyl CpG binding protein 2 (MECP2). Because overexpression of endogenous …
[PDF][PDF] Extensive homeostatic T cell phenotypic variation within the Collaborative Cross
The Collaborative Cross (CC) is a panel of reproducible recombinant inbred mouse strains
with high levels of standing genetic variation, affording an unprecedented opportunity to …
with high levels of standing genetic variation, affording an unprecedented opportunity to …