Muscarinic receptor activation facilitates the induction of synaptic plasticity and enhances
cognitive function. However, the specific muscarinic receptor subtype involved and the critical …

The formation and maintenance of spatial representations within hippocampal cell
assemblies is strongly dictated by patterns of inhibition from diverse interneuron populations. …

Phosphorylation or SUMOylation of the kainate receptor (KAR) subunit GluK2 have both
individually been shown to regulate KAR surface expression. However, it is unknown whether …

Kainate receptors (KARs) are ionotropic glutamate receptors that also activate noncanonical
G-protein-coupled signaling pathways to depress the slow afterhyperpolarization (sAHP). …

We have previously shown that spontaneous release of glutamate in the entorhinal cortex (EC)
is tonically facilitated via activation of presynaptic NMDA receptors (NMDAr) containing …

Hebbian synaptic plasticity at hippocampal Schaffer collateral synapses is tightly regulated
by postsynaptic small conductance (SK) channels that restrict NMDA receptor activity. SK …

Oscillatory network activity in cortical areas is seen as vital to physiological processes of
cognition, learning, and memory, and fundamental to disorders such as epilepsy. Increasing …

AMPA receptor (AMPAR) trafficking is a key determinant of synaptic strength and synaptic
plasticity. Under basal conditions, constitutive trafficking maintains surface AMPARs by …

NMDA receptors (NMDAr) are known to undergo recycling and lateral diffusion in postsynaptic
spines and dendrites. However, NMDAr are also present as autoreceptors on glutamate …

Muscarinic receptor activation facilitates the induction of synaptic plasticity and enhances
cognitive function. However, the specific muscarinic receptor subtype involved and the critical …