Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data
We engineered a machine learning approach, MSHub, to enable auto-deconvolution of gas
chromatography–mass spectrometry (GC–MS) data. We then designed workflows to enable …
chromatography–mass spectrometry (GC–MS) data. We then designed workflows to enable …
Optimisation of sampling parameters for standardised exhaled breath sampling
The lack of standardisation of breath sampling is a major contributing factor to the poor
repeatability of results and hence represents a barrier to the adoption of breath tests in clinical …
repeatability of results and hence represents a barrier to the adoption of breath tests in clinical …
[HTML][HTML] The cancer hub approach for upper gastrointestinal surgery during COVID-19 pandemic: outcomes from a UK cancer centre
JP Doyle, PH Patel, SLF Doran, LR Jiao… - Annals of surgical …, 2023 - Springer
Background The coronavirus disease 2019 (COVID-19) pandemic caused unprecedented
disruption to global healthcare delivery. In England, the majority of elective surgery was …
disruption to global healthcare delivery. In England, the majority of elective surgery was …
[HTML][HTML] Cross-platform mass spectrometry annotation in breathomics of oesophageal-gastric cancer
Disease breathomics is gaining importance nowadays due to its usefulness as non-invasive
early cancer detection. Mass spectrometry (MS) technique is often used for analysis of …
early cancer detection. Mass spectrometry (MS) technique is often used for analysis of …
[HTML][HTML] Enhanced recovery protocols after oesophagectomy
LJ Halliday, SR Markar, SLF Doran… - Journal of Thoracic …, 2017 - ncbi.nlm.nih.gov
The feasibility and safety of enhanced recovery protocols (ERP) have been demonstrated in
a large number of surgical specialties. Several studies have shown improved post-operative …
a large number of surgical specialties. Several studies have shown improved post-operative …
Algorithmic learning for auto-deconvolution of GC-MS data to enable molecular networking within GNPS
Gas chromatography-mass spectrometry (GC-MS) represents an analytical technique with
significant practical societal impact. Spectral deconvolution is an essential step for interpreting …
significant practical societal impact. Spectral deconvolution is an essential step for interpreting …
[HTML][HTML] The Diagnostic Accuracy of 18F-FGD-PET/CT for Cancer of the Gallbladder: A Retrospective Study
S Pericleous, SLF Doran… - World Journal of …, 2022 - thieme-connect.com
Background Gallbladder cancer has a poor prognosis and imaging can have variable
diagnostic accuracy. We assessed the ability of preoperative 18 F-fluorodeoxyglucose positron …
diagnostic accuracy. We assessed the ability of preoperative 18 F-fluorodeoxyglucose positron …
EGS P24 Management of oesophageal denture impaction and complications-a case series
SLF Doran, B Mohammadi… - British Journal of …, 2023 - academic.oup.com
Background Dentures are sometimes inadvertently ingested and can impact in the oesophagus.
This can lead to complications such as mediastinitis, perforation and major vascular …
This can lead to complications such as mediastinitis, perforation and major vascular …
EGS P04 Recent ten year experience of Boerhaave's Syndrome Management in a tertiary Oesophago-gastric Surgery Centre
A Ramdin, SLF Doran, YA Qureshi… - British Journal of …, 2023 - academic.oup.com
Background Oesophageal Perforation (OP) is a low incidence, high complexity
gastrointestinal surgical emergency with associated high mortality rates. A consequence of UK …
gastrointestinal surgical emergency with associated high mortality rates. A consequence of UK …
Off‐target effects of bacillus Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2: implications for protection against severe COVID‐19
…, J Dominguez, C Doran… - Clinical & …, 2022 - Wiley Online Library
Background and objectives Because of its beneficial off‐target effects against non‐mycobacterial
infectious diseases, bacillus Calmette–Guérin (BCG) vaccination might be an …
infectious diseases, bacillus Calmette–Guérin (BCG) vaccination might be an …