[HTML][HTML] Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization

…, T Delaveau, L Jourdren, S Le Crom, S Lemoine… - PloS one, 2008 - journals.plos.org
The asymmetric localization of mRNA plays an important role in coordinating posttranscriptional
events in eukaryotic cells. We investigated the peripheral mitochondrial localization of …

Estrogen receptor alpha mRNA in human skeletal muscles.

S Lemoine, P Granier, C Tiffoche… - Medicine and science …, 2003 - europepmc.org
Methods The highly sensitive technique of nested reverse transcriptase-polymerase chain
reaction (nested RT-PCR) was applied on a variety of tissue samples of both sexes: women (…

[HTML][HTML] THO/Sub2p functions to coordinate 3′-end processing with gene-nuclear pore association

…, E Kisseleva-Romanova, RK Gudipati, S Lemoine… - Cell, 2008 - cell.com
During transcription, proteins assemble sequentially with nascent RNA to generate a
messenger ribonucleoprotein particle (mRNP). The THO complex and its associated Sub2p …

Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways

…, S Vaur, I Sagot, F Coulpier, S Lemoine… - Genes & …, 2009 - genesdev.cshlp.org
Cells use strategic metabolites to sense the metabolome and accordingly modulate gene
expression. Here, we show that the purine and phosphate pathways are positively regulated …

Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells

…, A Gresset, A Schmitt, A Debbiche, S Lemoine… - Cancer discovery, 2019 - AACR
Patients affected by NF1 develop numerous cNFs. We present a mouse model that faithfully
recapitulates cNFs, identify a candidate cell type at their origin, analyze the steps involved in …

[HTML][HTML] Structure and properties of transcriptional networks driving selenite stress response in yeasts

…, V Fardeau, E Piccini, G Lelandais, V Tanty, S Lemoine… - BMC genomics, 2008 - Springer
Background Stress responses provide valuable models for deciphering the transcriptional
networks controlling the adaptation of the cell to its environment. We analyzed the …

[HTML][HTML] The central role of PDR1 in the foundation of yeast drug resistance

…, G Lelandais, A Oldfield, H Salin, S Lemoine… - Journal of Biological …, 2007 - ASBMB
The widespread pleiotropic drug resistance (PDR) phenomenon is well described as the
long term selection of genetic variants expressing constitutively high levels of membrane …

[HTML][HTML] IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans

…, L Orliaguet, I Hainault, C Blugeon, S Lemoine… - JCI insight, 2016 - ncbi.nlm.nih.gov
Hepatic fibrosis arises from inflammation in the liver initiated by resident macrophage activation
and massive leukocyte accumulation. Hepatic macrophages hold a central position in …

[HTML][HTML] Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection

…, S Goudey, E Ségéral, A Mohammad, S Lemoine… - Retrovirology, 2020 - Springer
Background Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-1)
replication that is tightly regulated both temporally and spatially. More than 50 different …

[HTML][HTML] Genome sequencing and transcriptome analysis of Trichoderma reesei QM9978 strain reveals a distal chromosome translocation to be responsible for loss of …

…, B Seiboth, SE Baker, S Le Crom, S Lemoine… - Biotechnology for …, 2017 - Springer
Background The hydrolysis of biomass to simple sugars used for the production of biofuels
in biorefineries requires the action of cellulolytic enzyme mixtures. During the last 50 years, …