Group 2 innate lymphoid cells (ILC2s) are essential to maintain tissue homeostasis. In cancer,
ILC2s can harbor both pro-tumorigenic and anti-tumorigenic functions, but we know little …

Natural killer (NK) cell activity is essential for initiating antitumor responses and may be
linked to immunotherapy success. NK cells and other innate immune components could be …

The increasing generation of population-level single-cell atlases has the potential to link
sample metadata with cellular data. Constructing such references requires integration of …

The increasing availability of large-scale single-cell atlases has enabled the detailed
description of cell states. In parallel, advances in deep learning allow rapid analysis of newly …

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression,
functioning in part by facilitating the degradation of target mRNAs. They have an established role …

These findings demonstrate antitumor activities of eosinophils in the metastatic tumor
microenvironment, suggesting that harnessing eosinophil activity may be a viable clinical strategy …

Differential expression analysis of RNA-seq is one of the most commonly performed
bioinformatics analyses. Transcript-level quantifications are inherently more uncertain than gene-…

Natural Killer ( NK ) cells have long been considered an important part of the anti‐tumor
immune response due to their potent cytolytic and cytokine‐secreting abilities. To date, a clear …

Despite increasing recognition of the importance of GM-CSF in autoimmune disease, it
remains unclear how GM-CSF is regulated at sites of tissue inflammation. Using GM-CSF fate …

Most cancer deaths are due to metastasis, and epithelial-to-mesenchymal transition (EMT)
plays a central role in driving cancer cell metastasis. EMT is induced by different stimuli, …