Background The fungal genus Aspergillus is of critical importance to humankind. Species
include those with industrial applications, important pathogens of humans, animals and crops, …

The uric acid/xanthine H + symporter, UapA, is a high-affinity purine transporter from the
filamentous fungus Aspergillus nidulans. Here we present the crystal structure of a genetically …

In this work we unmask a novel downregulation mechanism of the uric acid/xanthine transporter
UapA, the prototype member of the ubiquitous Nucleobase‐Ascorbate Transporter family…

The role of membrane lipids in modulating eukaryotic transporter assembly and function
remains unclear. We investigated the effect of membrane lipids in the structure and transport …

We investigated the role of all arrestin‐like proteins of A spergillus nidulans in respect to
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of the …

10.7554/eLife.20083.001 Filamentous fungi provide excellent systems for investigating the
role of the AP-2 complex in polar growth. Using Aspergillus nidulans, we show that AP-2 has …

The azgA gene of Aspergillus nidulans encodes a hypoxanthine-adenine-guanine transporter.
It has been cloned by a novel transposon methodology. The null phenotype of azgA was …

Biodesulfurization is a process that selectively removes sulfur from dibenzothiophene and
its derivatives. Several natural biocatalysts harboring the highly conserved desulfurization …

UapA, a uric acid–xanthine permease of Aspergillus nidulans, has been used as a
prototype to study structure–function relationships in the ubiquitous nucleobase–ascorbate …

The recent elucidation of crystal structures of a bacterial member of the NCS1 family, the
Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct …