User profiles for Soula Hédi

Hédi Soula

Professor of Computational Biology
Verified email at sorbonne-universite.fr
Cited by 1829

p-Cresyl sulfate promotes insulin resistance associated with CKD

…, R Vanholder, Y Dugenet, HA Soula… - Journal of the …, 2013 - journals.lww.com
The mechanisms underlying the insulin resistance that frequently accompanies CKD are
poorly understood, but the retention of renally excreted compounds may play a role. One such …

Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes

L Genser, D Aguanno, HA Soula, L Dong… - The Journal of …, 2018 - Wiley Online Library
Obesity and its metabolic complications are characterized by subclinical systemic and tissue
inflammation. In rodent models of obesity, inflammation and metabolic impairments are …

Vocal communication at the nest between mates in wild zebra finches: a private vocal duet?

JE Elie, MM Mariette, HA Soula, SC Griffith… - Animal Behaviour, 2010 - Elsevier
Bird vocal duets are joint displays where two individuals, generally a mated pair, produce
temporally coordinated vocalizations. Duets may contribute to pair bond maintenance, mate …

The acoustic expression of stress in a songbird: does corticosterone drive isolation-induced modifications of zebra finch calls?

EC Perez, JE Elie, CO Soulage, HA Soula… - Hormones and …, 2012 - Elsevier
Animal vocalizations convey multiple pieces of information about the sender. Some of them
are stable, such as identity or sex, but others are labile like the emotional or motivational state…

Chronic treatment with myo-inositol reduces white adipose tissue accretion and improves insulin sensitivity in female mice

ML Croze, RE Vella, NJ Pillon, HA Soula… - The journal of nutritional …, 2013 - Elsevier
Type 2 diabetes is a complex disease characterized by a state of insulin resistance in
peripheral tissues such as skeletal muscle, adipose tissue or liver. Some inositol isomers have …

[HTML][HTML] Impact of receptor clustering on ligand binding

BR Caré, HA Soula - BMC Systems Biology, 2011 - Springer
Background Cellular response to changes in the concentration of different chemical species
in the extracellular medium is induced by ligand binding to dedicated transmembrane …

[HTML][HTML] AhR activation defends gut barrier integrity against damage occurring in obesity

…, L Genser, E Brot-Laroche, C Poitou, H Soula… - Molecular …, 2020 - Elsevier
Objective Obesity is characterized by systemic and low-grade tissue inflammation. In the
intestine, alteration of the intestinal barrier and accumulation of inflammatory cells in the …

[HTML][HTML] Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity

…, M Arizono, UV Nägerl, H Soula… - PLoS computational …, 2019 - journals.plos.org
Astrocytes, a glial cell type of the central nervous system, have emerged as detectors and
regulators of neuronal information processing. Astrocyte excitability resides in transient …

[HTML][HTML] Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity

…, L Genser, M Fradet, HA Soula… - International journal of …, 2021 - nature.com
Objectives Altered enteroendocrine cell (EEC) function in obesity and type 2 diabetes is not
fully understood. Understanding the transcriptional program that controls EEC differentiation …

Spontaneous dynamics of asymmetric random recurrent spiking neural networks

H Soula, G Beslon, O Mazet - Neural Computation, 2006 - direct.mit.edu
In this letter, we study the effect of a unique initial stimulation on random recurrent networks
of leaky integrate-and-fire neurons. Indeed, given a stochastic connectivity, this so-called …