We present TrackMate, an open source Fiji plugin for the automated, semi-automated, and
manual tracking of single-particles. It offers a versatile and modular solution that works out of …

Particle tracking is of key importance for quantitative analysis of intracellular dynamic
processes from time-lapse microscopy image data. Because manually detecting and following …

Plasmodium, the parasite that causes malaria, is transmitted by a mosquito into the dermis
and must reach the liver before infecting erythrocytes and causing disease. We present here …

The common and persistent failures to translate promising preclinical drug candidates into
clinical success highlight the limited effectiveness of disease models currently used in drug …

Malaria parasites use antigenic variation to avoid immune clearance and increase the
duration of infection in the human host. Variation at the surface of P. falciparum-infected …

Deaf‐blindness in three distinct genetic forms of Usher type I syndrome (USH1) is caused
by defects in myosin VIIa, harmonin and cadherin 23. Despite being critical for hearing, the …

Emerging real-time techniques for imaging viral infections provide powerful tools for
understanding the dynamics of virus-host cell interactions. Here we labeled human …

Malaria is contracted when Plasmodium sporozoites are inoculated into the vertebrate host
during the blood meal of a mosquito. In infected mosquitoes, sporozoites are present in large …

Standardization of immunophenotyping procedures has become a high priority. We have
developed a suite of whole-blood, syringe-based assay systems that can be used to …

The nuclear pore complex (NPC) mediates nucleo-cytoplasmic transport of macromolecules
and is an obligatory point of passage and functional bottleneck in the replication of some …