User profiles for Sreelekshmy Mohandas
 | Sreelekshmy MohandasScientist, ICMR-National Institute of Virology Verified email at icmr.gov.in Cited by 1063 |
[HTML][HTML] Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques
The COVID-19 pandemic is a global health crisis that poses a great challenge to the public
health system of affected countries. Safe and effective vaccines are needed to overcome this …
health system of affected countries. Safe and effective vaccines are needed to overcome this …
[HTML][HTML] Pathogenicity of SARS-CoV-2 Omicron (R346K) variant in Syrian hamsters and its cross-neutralization with different variants of concern
S Mohandas, PD Yadav, G Sapkal, AM Shete… - …, 2022 - thelancet.com
Background SARS-CoV-2 Omicron variant is rampantly spreading across the globe. We
assessed the pathogenicity and immune response generated by BA.1.1 sub-lineage of SARS-…
assessed the pathogenicity and immune response generated by BA.1.1 sub-lineage of SARS-…
[HTML][HTML] Isolation of SARS-CoV-2 B. 1.1. 28.2 (P2) variant and pathogenicity comparison with D614G variant in hamster model
P Yadav, S Mohandas, P Sarkale, D Nyayanit… - Journal of infection and …, 2022 - Elsevier
Background Considering the potential threat from emerging Severe Acute Respiratory
Syndrome-Corona Virus-2 (SARS-CoV-2) variants and the rising COVID-19 cases, SARS-CoV-2 …
Syndrome-Corona Virus-2 (SARS-CoV-2) variants and the rising COVID-19 cases, SARS-CoV-2 …
[PDF][PDF] Immunogenicity and protective efficacy of BBV152, whole virion inactivated SARS-CoV-2 vaccine candidates in the Syrian hamster model
The availability of a safe and effective vaccine would be the eventual measure to deal with
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) threat. Here, we have …
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) threat. Here, we have …
[PDF][PDF] Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluation
…, GN Sapkal, A Shete-Aich, G Desphande, S Mohandas… - Iscience, 2021 - cell.com
We report the development and evaluation of safety and immunogenicity of a whole virion
inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminum hydroxide gel (…
inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminum hydroxide gel (…
[HTML][HTML] Development of indigenous IgG ELISA for the detection of anti-SARS-CoV-2 IgG
Methods: A total of 513 blood samples (131 positive, 382 negative for SARS-CoV-2) were
collected and tested by microneutralization test (MNT). Antigen stock of SARS-CoV-2 was …
collected and tested by microneutralization test (MNT). Antigen stock of SARS-CoV-2 was …
[HTML][HTML] SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters
S Mohandas, PD Yadav, A Shete, D Nyayanit… - Viruses, 2021 - mdpi.com
B.1.617 is becoming a dominant Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)
lineage worldwide with many sublineages, of which B.1.617.2 is designated as a …
lineage worldwide with many sublineages, of which B.1.617.2 is designated as a …
SARS CoV-2 variant B. 1.617. 1 is highly pathogenic in hamsters than B. 1 variant
PD Yadav, S Mohandas, AM Shete, DA Nyayanit… - BioRxiv, 2021 - biorxiv.org
Background The recent emergence of new SARS-CoV-2 lineage B.1.617 in India has been
associated with a surge in the number of daily infections. This variant has combination of …
associated with a surge in the number of daily infections. This variant has combination of …
[HTML][HTML] Nipah virus outbreak in Kerala State, India amidst of COVID-19 pandemic
We report here a Nipah virus (NiV) outbreak in Kozhikode district of Kerala state, India, which
had caused fatal encephalitis in a 12-year-old boy and the outbreak response, which led to …
had caused fatal encephalitis in a 12-year-old boy and the outbreak response, which led to …
[HTML][HTML] Isolation and characterization of SARS-CoV-2 Beta variant from UAE travelers
Background The emergence of SARS-CoV-2 variants in places where the virus is uncontained
poses a global threat from the perspective of public health and vaccine efficacy. Travel …
poses a global threat from the perspective of public health and vaccine efficacy. Travel …