User profiles for Sreenath Nair

Sreenath Sasidharan Nair

- Verified email at ebi.ac.uk - Cited by 4519

Sreenath Nandakumar Nair

- Verified email at stjude.org - Cited by 242

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

M Varadi, S Anyango, M Deshpande, S Nair… - Nucleic acids …, 2022 - academic.oup.com
The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk ) is an
openly accessible, extensive database of high-accuracy protein-structure predictions. …

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

…, M Radhakrishnan, M Tsenkov, S Nair… - Nucleic Acids …, 2024 - academic.oup.com
The AlphaFold Database Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk
) has significantly impacted structural biology by amassing over 214 million predicted …

PDBe: improved findability of macromolecular structure data in the PDB

…, A Mukhopadhyay, N Nadzirin, S Nair… - Nucleic acids …, 2020 - academic.oup.com
The Protein Data Bank in Europe (PDBe), a founding member of the Worldwide Protein Data
Bank (wwPDB), actively participates in the deposition, curation, validation, archiving and …

PDBe-KB: a community-driven resource for structural and functional annotations

…, J Berrisford, M Deshpande, SS Nair… - Nucleic Acids …, 2020 - academic.oup.com
The Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org ) is a
community-driven, collaborative resource for literature-derived, manually curated and …

Lorlatinib in a Child with ALK-Fusion–Positive High-Grade Glioma

…, BA Orr, O Campagne, S Dhanda, S Nair… - … England Journal of …, 2021 - Mass Medical Soc
Lorlatinib Response in ALK-Fusion–Positive Glioma A child near death with an ALK-fusion–positive
high-grade glioma refractory to standard treatment had a dramatic response when …

3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources

M Varadi, S Nair, I Sillitoe, G Tauriello, S Anyango… - …, 2022 - academic.oup.com
While scientists can often infer the biological function of proteins from their 3-dimensional
quaternary structures, the gap between the number of known protein sequences and their …

[HTML][HTML] Comprehensive collection and prediction of ABC transmembrane protein structures in the AI era of structural biology

H Tordai, E Suhajda, I Sillitoe, S Nair, M Varadi… - International Journal of …, 2022 - mdpi.com
The number of unique transmembrane (TM) protein structures doubled in the last four years,
which can be attributed to the revolution of cryo-electron microscopy. In addition, …

PDBe and PDBe‐KB: Providing high‐quality, up‐to‐date and integrated resources of macromolecular structures to support basic and applied research and education

…, GJ Kleywegt, WM Bueno, N Nadzirin, S Nair… - Protein …, 2022 - Wiley Online Library
The archiving and dissemination of protein and nucleic acid structures as well as their
structural, functional and biophysical annotations is an essential task that enables the broader …

[HTML][HTML] Adult stem cell deficits drive Slc29a3 disorders in mice

S Nair, AM Strohecker, AK Persaud, B Bissa… - Nature …, 2019 - nature.com
Mutations exclusively in equilibrative nucleoside transporter 3 (ENT3), the only intracellular
nucleoside transporter within the solute carrier 29 (SLC29) gene family, cause an expanding …

[BOOK][B] Restoration of breath: consciousness and performance

S Nair - 2007 - books.google.com
Breath is the flow of air between life and death. Breathing is an involuntary action that functions
as the basis of all human activities, intellectual, artistic, emotional and physical. Breathing …