Alterations of the CIB2 calcium-and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48

…, APJ Giese, K Lee, AA Indzhykulian, SP Nandamuri… - Nature …, 2012 - nature.com
Sensorineural hearing loss is genetically heterogeneous. Here, we report that mutations in
CIB2, which encodes a calcium- and integrin-binding protein, are associated with …

Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes

MA Conte, R Joshi, EC Moore, SP Nandamuri… - …, 2019 - academic.oup.com
Background African cichlid fishes are well known for their rapid radiations and are a model
system for studying evolutionary processes. Here we compare multiple, high-quality, …

Proximate and ultimate causes of variable visual sensitivities: insights from cichlid fish radiations

…, BE Dalton, D Escobar‐Camacho, SP Nandamuri - genesis, 2016 - Wiley Online Library
Animals vary in their sensitivities to different wavelengths of light. Sensitivity differences can
have fitness implications in terms of animals' ability to forage, find mates, and avoid predators…

Adult plasticity in African cichlids: rapid changes in opsin expression in response to environmental light differences

SP Nandamuri, MR Yourick, KL Carleton - Molecular ecology, 2017 - Wiley Online Library
Phenotypic plasticity allows organisms to adapt quickly to local environmental conditions
and could facilitate adaptive radiations. Cichlids have recently undergone an adaptive …

Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real‐time PCR analyses

…, D Escobar‐Camacho, SP Nandamuri… - Molecular ecology …, 2019 - Wiley Online Library
To determine the visual sensitivities of an organism of interest, quantitative reverse
transcription–polymerase chain reaction (qRT–PCR) is often used to quantify expression of the light‐…

Tbx2a Modulates Switching of RH2 and LWS Opsin Gene Expression

…, L Campello, C O'Brien, SP Nandamuri… - Molecular Biology …, 2020 - academic.oup.com
Sensory systems are tuned by selection to maximize organismal fitness in particular
environments. This tuning has implications for intraspecies communication, the maintenance of …

Movement of transposable elements contributes to cichlid diversity

…, MA Conte, M Malinsky, SP Nandamuri… - Molecular …, 2020 - Wiley Online Library
African cichlid fishes are a prime model for studying speciation mechanisms. Despite the
development of extensive genomic resources, it has been difficult to determine which sources …

[HTML][HTML] Multiple trans QTL and one cis-regulatory deletion are associated with the differential expression of cone opsins in African cichlids

SP Nandamuri, MA Conte, KL Carleton - BMC genomics, 2018 - Springer
Background Dissecting the genetic basis of phenotypic diversity is one of the fundamental
goals in evolutionary biology. Despite growing evidence for gene expression divergence …

Determination of the genetic architecture underlying short wavelength sensitivity in Lake Malawi cichlids

SP Nandamuri, BE Dalton, KL Carleton - Journal of Heredity, 2017 - academic.oup.com
African cichlids are an exemplary system to study organismal diversity and rapid speciation.
Species differ in external morphology including jaw shape and body coloration, but also …

A second locus contributing to the differential expression of the blue sensitive opsin SWS2A in Lake Malawi cichlids

SP Nandamuri, JE Schulte, MR Yourick, BA Sandkam… - Hydrobiologia, 2023 - Springer
African cichlids provide an ideal platform for studying genes responsible for mate choice and
species divergence. These highly speciose fishes vary in expression of seven distinct cone …