MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins

S Sengupta, JA den Boon, IH Chen… - Proceedings of the …, 2008 - National Acad Sciences
Using highly sensitive microarray-based procedures, we identified eight microRNAs (miRNAs)
showing robust differential expression between 31 laser-capture-microdissected …

Fundamental differences in cell cycle deregulation in human papillomavirus–positive and human papillomavirus–negative head/neck and cervical cancers

…, MA Newton, PF Lambert, JA Den Boon, S Sengupta… - Cancer research, 2007 - AACR
Human papillomaviruses (HPV) are associated with nearly all cervical cancers, 20% to 30%
of head and neck cancers (HNC), and other cancers. Because HNCs also arise in HPV-…

Random-set methods identify distinct aspects of the enrichment signal in gene-set analysis

MA Newton, FA Quintana, JA Den Boon, S Sengupta… - 2007 - projecteuclid.org
… study of nasopharyngeal carcinoma (NPC) used the proposed methodology for category
enrichment [Sengupta et al. (2006)]. NPC is a cancer of the nasopharynx that is responsible …

Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma

S Sengupta, JA Den Boon, IH Chen, MA Newton… - Cancer research, 2006 - AACR
To identify the molecular mechanisms by which EBV-associated epithelial cancers are
maintained, we measured the expression of essentially all human genes and all latent EBV …

[HTML][HTML] The microRNAs of Epstein–Barr virus are expressed at dramatically differing levels among cell lines

ZL Pratt, M Kuzembayeva, S Sengupta, B Sugden - Virology, 2009 - Elsevier
Epstein–Barr Virus (EBV) encodes multiple microRNAs (miRNAs) from two primary transcripts,
BHRF1 and the BARTs. The expression of BHRF1 miRNAs is dependent on the type of …

[HTML][HTML] Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema

…, JM Bolin, N Leng, S Sengupta… - PLoS computational …, 2013 - journals.plos.org
The salamander has the remarkable ability to regenerate its limb after amputation. Cells at
the site of amputation form a blastema and then proliferate and differentiate to regrow the limb…

MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells

S Sengupta, J Nie, RJ Wagner, C Yang, R Stewart… - Stem …, 2009 - academic.oup.com
Human embryonic stem (ES) cells exhibit a shorter G 1 cell cycle phase than most somatic
cells. Here, we examine the role of an abundant, human ES cell-enriched microRNA, miR-92b…

Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma

LE Dodd, S Sengupta, IH Chen, JA Den Boon… - … Biomarkers & Prevention, 2006 - AACR
Polymorphisms in nitrosamine metabolism, DNA repair, and immune response genes have
been associated with nasopharyngeal carcinoma (NPC). Studies have suggested …

Molecular detection and identification of influenza viruses by oligonucleotide microarray hybridization

S Sengupta, K Onodera, A Lai… - Journal of Clinical …, 2003 - Am Soc Microbiol
Microarrays of virus-specific oligonucleotides may provide a method of screening samples for
the presence or absence of a large variety of viruses simultaneously. Influenza viruses are …

3-D culture and endothelial cells improve maturity of human pluripotent stem cell-derived hepatocytes

H Ardalani, S Sengupta, V Harms, V Vickerman… - Acta biomaterialia, 2019 - Elsevier
Human-induced pluripotent stem cell (hiPSC)-derived hepatocytes (iHEP) offer an attractive
alternative to primary human hepatocytes (PHH) for drug toxicity studies, as PHHs are …