The role of astrocytes in dysregulation of blood-brain barrier (BBB) function following
ischemic stroke is not well understood. Here, we investigate the effects of restoring the repair …

Genome-wide association studies of schizophrenia (GWAS) have revealed the role of rare
and common genetic variants, but the functional effects of the risk variants remain to be …

Cilia are dynamic microtubule-based organelles present on the surface of many eukaryotic
cell types and can be motile or non-motile primary cilia. Cilia defects underlie a growing list of …

A palindrome in DNA is like a palindrome in language, but when read backwards, it is a
complement of the forward sequence; effectively, the two halves of a sequence complement …

Patients with schizophrenia and their relatives have reduced prevalence of rheumatoid
arthritis. Schizophrenia and rheumatoid arthritis genome-wide association studies also indicate …

Background: Peripheral ischemia caused by peripheral artery disease is associated with
systemic inflammation, which may aggravate underlying comorbidities such as atherosclerosis …

We previously presented the protein-protein interaction network of schizophrenia associated
genes, and from it, the drug-protein interactome which showed the drugs that target any of …

Low-grade gliomas (LGGs) are the most common brain tumor affecting children. We recently
reported an early phase clinical trial of a peptide-based vaccine, which elicited consistent …

The tumor suppressor genes EAF2 and p53 are frequently dysregulated in prostate cancers.
Recently, we reported that concurrent p53 nuclear staining and EAF2 downregulation were …

Background Elongation factor for RNA polymerase II 2 (ELL2) was reported as a putative
tumor suppressor in the prostate. ELL2 is frequently down-regulated in prostatic …