User profiles for Srinivas Abhishek Mutnuru
 | Srinivas Abhishek MutnuruPhD scholar Verified email at iiserb.ac.in Cited by 22 |
[PDF][PDF] Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer
Alternative splicing of vascular endothelial growth factor A (VEGFA) generates numerous
isoforms with unique roles in tumor angiogenesis, and investigating the underlying mechanism …
isoforms with unique roles in tumor angiogenesis, and investigating the underlying mechanism …
Interplay within tumor microenvironment orchestrates neoplastic RNA metabolism and transcriptome diversity
The heterogeneous population of cancer cells within a tumor mass interacts intricately with
the multifaceted aspects of the surrounding microenvironment. The reciprocal crosstalk …
the multifaceted aspects of the surrounding microenvironment. The reciprocal crosstalk …
PKM2 dictates the poised chromatin state of PFKFB3 promoter to enhance breast cancer progression
The hypoxic milieu is a critical modulator of aerobic glycolysis, yet the regulatory mechanisms
between the key glycolytic enzymes in hypoxic cancer cells are largely unchartered. In …
between the key glycolytic enzymes in hypoxic cancer cells are largely unchartered. In …
Epigenetic regulation during hypoxia and its implications in cancer
D Pant, SA Mutnuru, S Shukla - Metabolism and Epigenetic Regulation …, 2022 - Springer
Hypoxia is defined as a cellular stress condition caused by a decrease in oxygen below
physiologically normal levels. Cells in the core of a rapidly growing solid tumor are faced with …
physiologically normal levels. Cells in the core of a rapidly growing solid tumor are faced with …
Prolactin-induced AMPK stabilizes alveologenesis and lactogenesis through regulation of STAT5 signaling
SL Jinagal, P Shekhar, K Chandra, SA Mutnuru… - bioRxiv, 2022 - biorxiv.org
AMP-activated protein kinase (AMPK) is an evolutionarily conserved serine/threonine kinase
that regulates energy homeostasis at cellular and organismal levels. It has been shown to …
that regulates energy homeostasis at cellular and organismal levels. It has been shown to …
PKM2-mediated epigenetic reprogramming regulates hypoxic expression of PFKFB3 to promote breast cancer progression
The hypoxic milieu is a critical modulator of aerobic glycolysis, yet the regulatory mechanisms
existing between the key glycolytic enzymes in hypoxic cancer cells are largely unexplored…
existing between the key glycolytic enzymes in hypoxic cancer cells are largely unexplored…
[BOOK][B] Metabolism and epigenetic regulation: Implications in cancer
Metabolic programs of individuals are key determinants for disease susceptibility and
immune response. This book, edited by experts in the field, summarizes epigenetic signaling …
immune response. This book, edited by experts in the field, summarizes epigenetic signaling …