[HTML][HTML] IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral …
K Fink, L Martin, E Mukawera, S Chartier, X De Deken… - Cell research, 2013 - nature.com
Airway epithelial cells are key initial innate immune responders in the fight against respiratory
viruses, primarily via the secretion of antiviral and proinflammatory cytokines that act in an …
viruses, primarily via the secretion of antiviral and proinflammatory cytokines that act in an …
Pinpointing cysteine oxidation sites by high-resolution proteomics reveals a mechanism of redox-dependent inhibition of human STING
N Zamorano Cuervo, A Fortin, E Caron, S Chartier… - Science …, 2021 - science.org
Protein function is regulated by posttranslational modifications (PTMs), among which reversible
oxidation of cysteine residues has emerged as a key regulatory mechanism of cellular …
oxidation of cysteine residues has emerged as a key regulatory mechanism of cellular …
Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5
…, P Doyon, L Martin, MJ Servant, S Chartier - Journal of innate …, 2014 - karger.com
Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5)
are the main cytosolic sensors of single-stranded RNA viruses, including …
are the main cytosolic sensors of single-stranded RNA viruses, including …
[HTML][HTML] Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines
E Mukawera, S Chartier, V Williams, PJ Pagano… - Redox Biology, 2015 - Elsevier
Oxidative stress is considered a causative factor in carcinogenesis, but also in the
development of resistance to current chemotherapies. The appropriate usage of redox-modulating …
development of resistance to current chemotherapies. The appropriate usage of redox-modulating …
Pinpointing of cysteine oxidation sites in vivo by high-resolution proteomics reveals mechanism of redox-dependent inhibition of STING
NZ Cuervo, A Fortin, E Caron, S Chartier, N Grandvaux - bioRxiv, 2020 - biorxiv.org
Protein function is regulated by post-translational modifications, among which reversible
oxidation of Cys (Cys ox-PTM) emerged as a key regulatory mechanism of cellular responses. …
oxidation of Cys (Cys ox-PTM) emerged as a key regulatory mechanism of cellular responses. …
Enrichment of oxidised peptides of oxidised allows identification of oxidized cysteine residues in signaling proteins in vivo
…, N Grandvaux, A Fortin, S Chartier - Free Radical Biology and …, 2018 - Elsevier
Detection of oxidative post-translational modifications (ox-PTMs) of Cys residues in
mammalian signaling proteins in vivo is one of the current challenges in redox biology. Ox-PTM …
mammalian signaling proteins in vivo is one of the current challenges in redox biology. Ox-PTM …
Regulation of the antiviral response by redox metabolism
F Audray, Z Natalia, H Alex, C Stéfany, E Caron… - Free Radical Biology …, 2018 - Elsevier
The antiviral response elicited by virus recognition is mediated by multiple signaling cascades
subjected to highly stringent regulatory mechanisms. Post-translational modifications (…
subjected to highly stringent regulatory mechanisms. Post-translational modifications (…
Identification of oxidized cysteine residues in signaling proteins in vivo
Z Natalia, F Audray, C Stefany, G Nathalie - Free Radical Biology and …, 2018 - Elsevier
Detection of oxidative post-translational modifications (ox-PTMs) of Cys residues in
mammalian signaling proteins in vivo is one of the current challenges in redox biology. Ox-PTM …
mammalian signaling proteins in vivo is one of the current challenges in redox biology. Ox-PTM …
IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH Oxidase-mediated airway antiviral response
K Fink, L Martin, E Mukawera, S Chartier… - Cell …, 2014 - ncbi.nlm.nih.gov
… Karin Fink, 1, 2 Lydie Martin, 1 Esperance Mukawera, 1 Stéfany Chartier, 1 Xavier De
Deken, 3 Emmanuelle Brochiero, 1, 4 Françoise Miot, 3 and Nathalie Grandvaux 1, 2 …
Deken, 3 Emmanuelle Brochiero, 1, 4 Françoise Miot, 3 and Nathalie Grandvaux 1, 2 …
Novel Regulatory Mechanism of STAT1 through Redox Post-translational Modification of Cysteines
A Harrison, A Fortin, N Zamorano, S Chartier… - Free Radical Biology …, 2017 - Elsevier
STAT1 plays a central role in the immune system, in which it mediates signaling induced by
different cytokines, including type I (α/β) and type II Interferon (IFN), and regulates …
different cytokines, including type I (α/β) and type II Interferon (IFN), and regulates …