In this study, the dynamically folded conformation of squalene (SQ) is taken advantage of to
link this natural compound to the anticancer nucleoside analogue gemcitabine (gem) in …

Endosomal sorting complexes for transport-III (ESCRT-III) assemble in vivo onto
membranes with negative Gaussian curvature. How membrane shape influences ESCRT-III …

Septins are cytoskeletal filaments that assemble at the inner face of the plasma membrane.
They are localized at constriction sites and impact membrane remodeling. We report in vitro …

Solubilization of integral membrane proteins in aqueous solutions requires the presence of
amphiphilic molecules like detergents. The transmembrane region of the proteins is then …

The degree of compaction of the eukaryotic chromatin in vivo and in vitro is highly sensitive
to the ionic environment. We address the question of the effect of multivalent ions on the …

Nucleosome core particles correspond to the structural units of eukaryotic chromatin. They
are charged colloids, 101 Å in diameter and 55 Å in length, formed by the coiling of a 146/147 …

La chromatine, formée de l’enroulement d’ADN autour d’un cœur d’histones, s’organise
suivant différents niveaux de compaction : de la particule cœur de nucléosome (NCP pour …

… Aurélie Bertin and Stéphanie Mangenot have equally contributed to the workco-senior …
Aurélie Bertin and Stéphanie Mangenot have equally contributed to the workco-senior authors …

The chromatophores of Rhodobacter (Rb.) sphaeroides represent a minimal bio-energetic
system, which efficiently converts light energy into usable chemical energy. Despite extensive …

AFM has developed into a powerful tool in structural biology, providing topographs of proteins
under close-to-native conditions and featuring an outstanding signal/noise ratio. However, …