Development of a genetic toolset for the highly engineerable and metabolically versatile Acinetobacter baylyi ADP1

BW Biggs, SR Bedore, E Arvay, S Huang… - Nucleic Acids …, 2020 - academic.oup.com
One primary objective of synthetic biology is to improve the sustainability of chemical
manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources, …

[HTML][HTML] Removal of aromatic inhibitors produced from lignocellulosic hydrolysates by Acinetobacter baylyi ADP1 with formation of ethanol by Kluyveromyces …

A Singh, SR Bedore, NK Sharma, SA Lee… - Biotechnology for …, 2019 - Springer
Background Lignocellulosic biomass is an attractive, inexpensive source of potentially
fermentable sugars. However, hydrolysis of lignocellulose results in a complex mixture containing …

Regulation of l- and d-Aspartate Transport and Metabolism in Acinetobacter baylyi ADP1

SR Bedore, AL Schmidt, LE Slarks… - Applied and …, 2022 - Am Soc Microbiol
The regulated uptake and consumption of d-amino acids by bacteria remain largely unexplored,
despite the physiological importance of these compounds. Unlike other characterized …

Natural transformation as a tool in Acinetobacter baylyi: Streamlined engineering and mutational analysis

SR Bedore, EL Neidle, I Pardo, J Luo, AC Baugh… - Methods in …, 2023 - Elsevier
Natural transformation and homologous recombination in a soil bacterium, Acinetobacter
baylyi ADP1, occur with exceptionally high efficiency. These genetic features can be …

Natural transformation as a tool in Acinetobacter baylyi: Evolution by amplification of gene copy number

I Pardo, SR Bedore, MP Tumen-Velasquez… - Methods in …, 2023 - Elsevier
For many years, the natural competency of Acinetobacter baylyi ADP1 facilitated studies of
bacterial metabolism, biochemistry, and physiology. With the advent of synthetic biology, new …

Characterization of highly ferulate-tolerant Acinetobacter baylyi ADP1 isolates by a rapid reverse engineering method

J Luo, EA McIntyre, SR Bedore, V Santala… - Applied and …, 2022 - Am Soc Microbiol
Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of
microbial hosts. Evolved strains typically contain numerous mutations that can be revealed by …

Metabolic expansion in Acinetobacter baylyi ADP1 for enhanced aromatic compound catabolism

SR Bedore - 2021 - search.proquest.com
Acinetobacter baylyi ADP1 degrades many aromatic compounds and has a uniquely tractable
genetic system. Recent interest in aromatic compound metabolism stems from diverse …

The Overuse of C. Difficile Testing Among Autologous Transplant Patients with Melphalan Conditioning: A Single Center Experience

J Dickey, M Standridge, S Desai, I Pavkov, S Bedore… - Blood, 2023 - Elsevier
Introduction: Melphalan is a common chemotherapy agent used as conditioning prior to
autologous stem cell transplants (Auto SCT). Most frequent side effects are gastrointestinal (GI), …

[HTML][HTML] Whole-retina reduced electrophysiological activity in mice bearing retina-specific deletion of vesicular acetylcholine transporter

J Bedore, AC Martyn, AKC Li, EA Dolinar, IS McDonald… - Plos one, 2015 - journals.plos.org
Background Despite rigorous characterization of the role of acetylcholine in retinal
development, long-term effects of its absence as a neurotransmitter are unknown. One of the …

Language sample analysis in Spanish-speaking children: Methodological considerations

…, MA Restrepo, L Bedore, E Peña, R Anderson - Language, Speech, and …, 2000 - ASHA
The purposes of this article are (a) to discuss issues related to the selection and development
of language assessment procedures for children who speak Spanish and English based …