The recent emergence of B.1.1.529, the Omicron variant 1 , 2 , has raised concerns of
escape from protection by vaccines and therapeutic antibodies. A key test for potential …

For the third time in as many decades, a zoonotic coronavirus has crossed species to infect
human populations. This virus, provisionally called 2019-nCoV, was first identified in Wuhan, …

Although coronaviruses were first identified nearly 60 years ago, they only received notoriety
in 2003 when one of their members was identified as the aetiological agent of severe acute …

Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like
spikes that project from their surface, an unusually large RNA genome, and a unique …

Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild, cold…

The present outbreak of lower respiratory tract infections, including respiratory distress
syndrome, is the third spillover, in only two decades, of an animal coronavirus to humans …

During the summer of 2012, in Jeddah, Saudi Arabia, a hitherto unknown coronavirus (CoV)
was isolated from the sputum of a patient with acute pneumonia and renal failure (1, 2). The …

Highly pathogenic human respiratory coronaviruses cause acute lethal disease characterized
by exuberant inflammatory responses and lung damage. However, the factors leading to …

Infection of humans with the severe acute respiratory syndrome coronavirus (SARS-CoV)
results in substantial morbidity and mortality, with death resulting primarily from respiratory …

… Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong,
Prince of Wales Hospital, New Territories, Hong … Prof Stanley Perlman, MD Stanley Perlman …