MicroRNAs in the development of resistance to antiseizure drugs and their potential as biomarkers in pharmacoresistant epilepsy

…, P Jabandziev, H Oslejskova, O Slaby, S Aulicka - …, 2021 - Wiley Online Library
Although many new antiseizure drugs have been developed in the past decade, approximately
30%–40% of patients remain pharmacoresistant. There are no clinical tools or guidelines …

[HTML][HTML] Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?

…, R Labounek, C Lenglet, A Paulson, S Aulicka… - Neuroimage, 2021 - Elsevier
White matter bundle segmentation using diffusion MRI fiber tractography has become the
method of choice to identify white matter fiber pathways in vivo in human brains. However, like …

Cytokine-chemokine profiles in the hippocampus of patients with mesial temporal lobe epilepsy and hippocampal sclerosis

S Aulická, K Česká, J Šána, F Siegl, E Brichtová… - Epilepsy Research, 2022 - Elsevier
Purpose Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is the most
common drug-resistant epilepsy. Despite major advances in epilepsy research, the …

[HTML][HTML] Multivariate linear mixture models for the prediction of febrile seizure risk and recurrence: a prospective case–control study

J Papež, R Labounek, P Jabandžiev, K Česká… - Scientific reports, 2023 - nature.com
Our goal was to identify highly accurate empirical models for the prediction of the risk of
febrile seizure (FS) and FS recurrence. In a prospective, three-arm, case–control study, we …

CCL2/MCP-1, interleukin-8, and fractalkine/CXC3CL1: Potential biomarkers of epileptogenesis and pharmacoresistance in childhood epilepsy

K Česká, J Papež, H Ošlejšková, O Slabý… - European Journal of …, 2023 - Elsevier
Objective The pathophysiological processes leading to epileptogenesis and pharmacoresistance
in epilepsy have been the subject of extensive preclinical and clinical research. The …

[HTML][HTML] Current Management of Generalized Convulsive Status Epilepticus in Children

Š Aulická - Children, 2022 - mdpi.com
Generalized convulsive status epilepticus (GCSE) in pediatric patients is an emergency
condition with high morbidity and mortality and potentially irreversible brain damage, leading to …

[HTML][HTML] Regional incidence of inflammatory bowel disease in a Czech pediatric population: 16 years of experience (2002–2017)

…, M Novackova, M Urik, S Aulicka… - Journal of Pediatric …, 2020 - journals.lww.com
Objectives: Inflammatory bowel disease (IBD) is today a global disease, the incidence of
which is growing in the pediatric population. This prospective study aims to decipher IBD …

[HTML][HTML] Autosomal dominant temporal lobe epilepsy associated with heterozygous reelin mutation: 3 T brain MRI study with advanced neuroimaging methods

K Česká, Š Aulická, O Horák, P Danhofer… - Epilepsy & Behavior …, 2019 - Elsevier
Purpose Autosomal dominant lateral temporal epilepsy (ADLTE) is a genetic focal epilepsy
syndrome characterized by focal seizures with dominant auditory symptomatology. We …

The direct costs of Dravet's syndrome before and after diagnosis assessment

K Česká, L Český, H Ošlejšková, Š Aulická - Neuropediatrics, 2021 - thieme-connect.com
The objective of this study was to estimate the direct cost before and after diagnosis
assessment in patients with Dravet's syndrome (DS). The basis of the economic study was to …

[HTML][HTML] Prognostic factors and seizure outcome in posterior reversible encephalopathy syndrome (PRES) in children with hematological malignancies and bone …

P Danhofer, M Tomečková, D Černá, D Zapletalová… - Seizure, 2019 - Elsevier
Purpose The aim of this study was to evaluate seizure outcome in children with hematological
malignancies and PRES and to identify prognostic factors that could help manage the …