BACKGROUND: Asthma is characterized by increased airway narrowing in response to
nonspecific stimuli. The disorder is influenced by both environmental and genetic factors. …

Exosomes and the invariant NKT (iNKT) immune cell ligand α-galactosylceramide (αGC)
may offer novel tools for cancer immunotherapy. In this study, we investigated whether …

Extracellular vesicles (EV), including exosomes and microvesicles (MV), represent a rapidly
expanding field of research with diagnostic and therapeutic applications. Although many …

Background Malignant pleural and peritoneal mesotheliomas are rare malignancies with
unacceptable poor prognoses and limited treatment options. The genomic landscape is mainly …

In recent years exosomes have emerged as potent stimulators of immune responses and as
agents for cancer therapy. Exosomes can carry a broad variety of immunostimulatory …

Exosomes are small 40-120 nm vesicles secreted by nearly all cells and are an important
form of intercellular communication. Exosomes are abundant, stable, and highly bioavailable …

Some breast tumors metastasize aggressively whereas others remain dormant for years.
The mechanism governing metastatic dormancy remains largely unknown. Through high-…

Peptide-loaded exosomes are promising cancer treatment vehicles; however, moderate T
cell responses in human clinical trials indicate a need to further understand exosome-induced …

Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up
to 80% of the MPM cases are linked to asbestos exposure. Even though its use has been …

Invasive urinary bladder cancer shows high recurrence rates after cystectomy even with
apparent complete downstaging at cystectomy. Exosomes are nano-sized vesicles important in …