A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions

S Jehle, N Kunowska, N Benlasfer… - Molecular systems …, 2022 - embopress.org
Protein kinases play an important role in cellular signaling pathways and their dysregulation
leads to multiple diseases, making kinases prime drug targets. While more than 500 human …

A new role for FBP21 as regulator of Brr2 helicase activity

LM Henning, KF Santos, J Sticht, S Jehle… - Nucleic Acids …, 2017 - academic.oup.com
Splicing of eukaryotic pre-mRNA is carried out by the spliceosome, which assembles
stepwise on each splicing substrate. This requires the concerted action of snRNPs and non-snRNP …

Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and function

…, A Feichtner, E Jany-Luig, S Jehle… - Life Science …, 2023 - life-science-alliance.org
NF2 (moesin–ezrin–radixin-like [MERLIN] tumor suppressor) is frequently inactivated in
cancer, where its NF2 tumor suppressor functionality is tightly coupled to protein conformation. …

[HTML][HTML] The CD177 c.1291A Allele Leads to a Loss of Membrane Expression and Mimics a CD177-Null Phenotype

A Traum, S Jehle, Y Waxmann, AS Litmeyer… - International Journal of …, 2024 - mdpi.com
CD177 is a glycosyl phosphatidyl inositol (GPI)-linked, neutrophil-specific glycoprotein that
in 3–5% of normal individuals is absent from all neutrophils. The molecular mechanism …

[HTML][HTML] Significant neutropenia induced by metamizole dependent neutrophil antibodies

BR Curtis, S Jehle, G Bein, B Bayat, UJ Sachs - Blood Transfusion, 2024 - ncbi.nlm.nih.gov
Dear Sir, Neutrophils play an important role for the elimination of pathogens during infections.
Neutropenia results either from enhanced peripheral neutrophil destruction or decreased …

An unusual strategy for the anoxic biodegradation of phthalate

C Ebenau-Jehle, M Mergelsberg, S Fischer… - The ISME …, 2017 - academic.oup.com
In the past two decades, the study of oxygen-independent degradation of widely abundant
aromatic compounds in anaerobic bacteria has revealed numerous unprecedented …

Sulfate reduction in methanogenic bioreactors

JWHOE Stefanie, A Visser, LWH Pol… - FEMS Microbiology …, 1994 - academic.oup.com
In the anaerobic treatment of sulfate-containing wastewater, sulfate reduction interferes with
methanogenesis. Both mutualistic and competitive interactions between sulfate-reducing …

Molecular functions of the chromatin-remodeling factor DPF3 and its implication for myogenesis

K Bellmann - 2016 - refubium.fu-berlin.de
… Genetics, I would like to thank especially Stefanie Jehle and Dr. Jonathan Woodsmith for
the good times I spent in the Stelzl group. Stefanie Jehle did a great job in introducing me into …

[PDF][PDF] A positive relationship between ant biodiversity (Hymenoptera: Formicidae) and rate of scavenger-mediated nutrient redistribution along a disturbance gradient …

…, J Walsh, S Weigl, PG Craze, R Jehle… - Myrmecological …, 2011 - researchgate.net
Human modification of pristine habitats almost always leads to the local extinction of a
subset of the species present. This means that the ecosystem processes carried out by the …

Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5a

N Elumalai, A Berg, K Natarajan… - Angewandte …, 2015 - Wiley Online Library
… We extend our thanks to Martin Gräber, Stefanie Jehle, and Stephanie Häfner for experimental
support and fruitful discussions. We extend our thanks to Lothar Hennighausen (National …