Background The World Health Organization’s strategy to halve snakebite mortality and
morbidity by 2030 includes an emphasis on a risk-benefit process assessing the preclinical …

Background Soil-transmitted helminths (STH) infect more than 2 billion humans worldwide,
causing significant morbidity in children. There are few data on the epidemiology and risk …

… Author links open overlay panel Stefanie K. Menzies a b , Rachel H. Clare a b , Chunfang …
Stefanie K Menzies: Methodology, Investigation, Formal analysis, Data curation, Writing – …

To improve the characterization of snake venom protein profiles, we report the application of
a new generation of proteomic methodology to deeply characterize complex protein …

New drugs against Trypanosoma brucei, the causative agent of Human African Trypanosomiasis,
are urgently needed to replace the highly toxic and largely ineffective therapies …

Phenotypic assays are becoming increasingly more common among drug discovery practices,
expanding drug target diversity as lead compounds identified through such screens are …

Snakebite envenoming is a major global public health concern for which improved therapies
are urgently needed. The antigenic diversity present in snake venom toxins from various …

Snakebite is a neglected tropical disease that causes high rates of global mortality and
morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects …

Current drugs to treat African sleeping sickness are inadequate and new therapies are
urgently required. As part of a medicinal chemistry programme based upon the simplification of …

Background Snakebite is a major public health concern in Eswatini, where treatment relies
upon one antivenom—SAIMR Polyvalent. Although effective in treating snakebite, SAIMR …