The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although the …

Mechanical signaling plays an important role in cell physiology and pathology. Many cell
types, including neurons and glial cells, respond to the mechanical properties of their …

Mechanism-oriented studies of EAE rely mostly on gene-modified mice on the C57BL/6
background. Here we report that MP4-induced EAE displays characteristic differences in CNS …

Aberrant immune responses represent the underlying cause of central nervous system (CNS)
autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk …

Batoulis H, Recks MS, Addicks K, Kuerten S. Experimental autoimmune encephalomyelitis
– achievements and prospective advances. APMIS 2011; 119: 819–30. Multiple sclerosis (MS…

While the role of T cells has been studied extensively in multiple sclerosis (MS), the pathogenic
contribution of B cells has only recently attracted major attention, when it was shown that …

Despite continuous interest in multiple sclerosis (MS) research, there is still a lack of
neuroprotective strategies, because the main focus has remained on modulating the immune …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS),
with characteristic inflammatory lesions and demyelination. The clinical benefit of cell-…

Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE)
have long been regarded as primarily T helper cell type 1-mediated diseases. However…

… also defines the magnitude of pathology (Stefanie Kuerten, manuscript in preparation). … and
amplification of the immune attack on the brain (Stefanie Kuerten, manuscript in preparation). …