We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains
and find extensive strain-specific haplotype variation. We identify and characterize 2,567 …

The recent introductions of low-cost, long-read, and read-cloud sequencing technologies
coupled with intense efforts to develop efficient algorithms have made affordable, high-quality …

Understanding the mechanisms driving lineage-specific evolution in both primates and
rodents has been hindered by the lack of sister clades with a similar phylogenetic structure …

Comparing multiple related genomes can help to improve their structural annotation. The
accuracy and consistency of the predicted exon–intron structures of the protein coding genes …

As the tree of life is populated with sequenced genomes ever more densely, the new challenge
is the accurate and consistent annotation of entire clades of genomes. In my dissertation, …

Alignment is possibly the most fundamental problem in genomics. The alignment problem is
to establish a mapping between the letters of a set of sequences that approximates some …

Understanding the mechanisms driving lineage-specific evolution in both primates and
rodents has been hindered by the lack of sister clades with a similar phylogenetic structure …

Since the application of new high-throughput sequencing methods (next-generation sequencing)
to genome sequencing, the number of sequenced eukaryotic genomes is increasing …

Glacitectonic deformation in the Upper Weichselian led to the tectonic framework of large-scale
folds and displaced thrust sheets of Maastrichtian (Upper Cretaceous) chalk and …

In contrast to the western honey bee, Apis mellifera, other honey bee species have been
largely neglected despite their importance and diversity. The genetic basis of the evolutionary …