User profiles for Stefano Severi
 | Stefano SeveriAssociate Professor, Bioengineering, University of Bologna Verified email at unibo.it Cited by 4128 |
Silybin, a new iron-chelating agent
…, F Ghelfi, R Grandi, M Saladini, S Severi… - Journal of inorganic …, 2001 - Elsevier
Silybin, a natural occurring flavolignan isolated from the fruits of Silibum marianum, has been
reported to exert antioxidant and free radical scavenging abilities. It was suggested to act …
reported to exert antioxidant and free radical scavenging abilities. It was suggested to act …
Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block
Human-based modelling and simulations are becoming ubiquitous in biomedical science
due to their ability to augment experimental and clinical investigations. Cardiac …
due to their ability to augment experimental and clinical investigations. Cardiac …
Computational models of ventricular-and atrial-like human induced pluripotent stem cell derived cardiomyocytes
The clear importance of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs)
as an in-vitro model highlights the relevance of studying these cells and their …
as an in-vitro model highlights the relevance of studying these cells and their …
Role of 18FDG PET/CT in patients treated with 177Lu-DOTATATE for advanced differentiated neuroendocrine tumours
Purpose The prognostic value of FDG PET for neuroendocrine tumours (NETs) has been
reported. In this study we evaluated the role of FDG PET in predicting response and …
reported. In this study we evaluated the role of FDG PET in predicting response and …
Computational analysis of the human sinus node action potential: model development and effects of mutations
Key points We constructed a comprehensive mathematical model of the spontaneous electrical
activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent Severi–…
activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent Severi–…
[HTML][HTML] Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy
Introduction Hypertrophic cardiomyopathy (HCM) is a cause of sudden arrhythmic death,
but the understanding of its pro-arrhythmic mechanisms and an effective pharmacological …
but the understanding of its pro-arrhythmic mechanisms and an effective pharmacological …
Treatment with the Radiolabelled Somatostatin Analog 177Lu-DOTATATE for Advanced Pancreatic Neuroendocrine Tumors
M Sansovini, S Severi, A Ambrosetti, M Monti… - …, 2013 - karger.com
Background: We evaluated the activity and safety profile of 177 Lu-DOTATATE peptide
receptor radionuclide therapy (Lu-PRRT) in patients with advanced G1-G2 pancreatic …
receptor radionuclide therapy (Lu-PRRT) in patients with advanced G1-G2 pancreatic …
An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation
S Severi, M Fantini, LA Charawi… - The Journal of …, 2012 - Wiley Online Library
Key points • Computational models of the electrical activity of sinoatrial cells (SANCs) have
been proposed to gain a deeper understanding of the cellular basis of cardiac pacemaking. • …
been proposed to gain a deeper understanding of the cellular basis of cardiac pacemaking. • …
PRRT genomic signature in blood for prediction of 177Lu-octreotate efficacy
…, MS Kidd, A Singh, WA Van Der Zwan, S Severi… - European journal of …, 2018 - Springer
Background Peptide receptor radionuclide therapy (PRRT) utilizes somatostatin receptor (SSR)
overexpression on neuroendocrine tumors (NET) to deliver targeted radiotherapy. …
overexpression on neuroendocrine tumors (NET) to deliver targeted radiotherapy. …
Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes
…, E Torre, G Mostacciuolo, S Severi… - Cardiovascular …, 2017 - academic.oup.com
Aims Calmodulin (CaM) is a small protein, encoded by three genes (CALM1-3), exerting
multiple Ca 2+ -dependent modulatory roles. A mutation (F142L) affecting only one of the six …
multiple Ca 2+ -dependent modulatory roles. A mutation (F142L) affecting only one of the six …