Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
…, SB Ethridge, MM Soller, SP Petkova… - Genes, brain and …, 2022 - Wiley Online Library
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance
…, VA Minie, AM Tran, SP Petkova… - Proceedings of the …, 2020 - National Acad Sciences
Oxytocin increases the salience of both positive and negative social contexts and it is thought
that these diverse actions on behavior are mediated in part through circuit-specific action. …
that these diverse actions on behavior are mediated in part through circuit-specific action. …
[HTML][HTML] Excessive laughter-like vocalizations, microcephaly, and translational outcomes in the Ube3a deletion rat model of Angelman syndrome
Angelman syndrome (AS) is a rare genetic neurodevelopmental disorder characterized by
intellectual disabilities, motor and balance deficits, impaired communication, and a happy, …
intellectual disabilities, motor and balance deficits, impaired communication, and a happy, …
[HTML][HTML] Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats
EL Berg, LR Pedersen, MC Pride, SP Petkova… - Translational …, 2020 - nature.com
Epidemiological studies consistently implicate traffic-related air pollution (TRAP) and/or
proximity to heavily trafficked roads as risk factors for developmental delays and …
proximity to heavily trafficked roads as risk factors for developmental delays and …
[HTML][HTML] Neuroanatomy and behavior in mice with a haploinsufficiency of AT-rich interactive domain 1B (ARID1B) throughout development
Background One of the causal mechanisms underlying neurodevelopmental disorders (NDDs)
is chromatin modification and the genes that regulate chromatin. AT-rich interactive …
is chromatin modification and the genes that regulate chromatin. AT-rich interactive …
Gait as a quantitative translational outcome measure in Angelman syndrome
Angelman syndrome (AS) is a genetic neurodevelopmental disorder characterized by
developmental delay, lack of speech, seizures, intellectual disability, hypotonia, and motor …
developmental delay, lack of speech, seizures, intellectual disability, hypotonia, and motor …
[HTML][HTML] Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman syndrome
Background Angelman Syndrome (AS) is a rare neurodevelopmental disorder for which there
is currently no cure or effective therapeutic. Since the genetic cause of AS is known to be …
is currently no cure or effective therapeutic. Since the genetic cause of AS is known to be …
[HTML][HTML] Tracing development of song memory with fMRI in zebra finches after a second tutoring experience
P Arya, SP Petkova, PP Kulkarni, NH Kolodny… - Communications …, 2023 - nature.com
Sensory experiences in early development shape higher cognitive functions such as language
acquisition in humans and song learning in birds. Zebra finches (Taeniopygia guttata) …
acquisition in humans and song learning in birds. Zebra finches (Taeniopygia guttata) …
[HTML][HTML] Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation
Neurobehavioral studies have produced contradictory findings concerning the function of
neurogenesis in the adult dentate gyrus. Previous studies have proved inconsistent across …
neurogenesis in the adult dentate gyrus. Previous studies have proved inconsistent across …
[HTML][HTML] An in vivo cell-based delivery platform for zinc finger artificial transcription factors in pre-clinical animal models
…, A Adhikari, N Copping, SP Petkova… - Frontiers in Molecular …, 2022 - frontiersin.org
Zinc finger, transcription activator-like effectors, and CRISPR/Cas9 therapies to regulate gene
expression are becoming viable strategies to treat genetic disorders, although effective in …
expression are becoming viable strategies to treat genetic disorders, although effective in …