Imaging breast cancer using hyperpolarized carbon-13 MRI
…, J Kaggie, A Chhabra, S Ursprung… - Proceedings of the …, 2020 - National Acad Sciences
Our purpose is to investigate the feasibility of imaging tumor metabolism in breast cancer
patients using 13 C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized 13 C …
patients using 13 C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized 13 C …
[HTML][HTML] Common pitfalls and recommendations for using machine learning to detect and prognosticate for COVID-19 using chest radiographs and CT scans
Abstract Machine learning methods offer great promise for fast and accurate detection and
prognostication of coronavirus disease 2019 (COVID-19) from standard-of-care chest …
prognostication of coronavirus disease 2019 (COVID-19) from standard-of-care chest …
[HTML][HTML] Radiomics of computed tomography and magnetic resonance imaging in renal cell carcinoma—a systematic review and meta-analysis
S Ursprung, L Beer, A Bruining, R Woitek… - European …, 2020 - Springer
Objectives (1) To assess the methodological quality of radiomics studies investigating
histological subtypes, therapy response, and survival in patients with renal cell carcinoma (RCC) …
histological subtypes, therapy response, and survival in patients with renal cell carcinoma (RCC) …
[HTML][HTML] Tissue-specific and interpretable sub-segmentation of whole tumour burden on CT images by unsupervised fuzzy clustering
Background: Cancer typically exhibits genotypic and phenotypic heterogeneity, which can
have prognostic significance and influence therapy response. Computed Tomography (CT)-…
have prognostic significance and influence therapy response. Computed Tomography (CT)-…
[HTML][HTML] Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
…, JV Schaefer, U Karakus, S Ursprung… - Nature …, 2021 - nature.com
The V3 loop of the HIV-1 envelope (Env) protein elicits a vigorous, but largely non-neutralizing
antibody response directed to the V3-crown, whereas rare broadly neutralizing antibodies …
antibody response directed to the V3-crown, whereas rare broadly neutralizing antibodies …
Association of clinician diagnostic performance with machine learning–based decision support systems: a systematic review
Importance An increasing number of machine learning (ML)–based clinical decision support
systems (CDSSs) are described in the medical literature, but this research focuses almost …
systems (CDSSs) are described in the medical literature, but this research focuses almost …
[HTML][HTML] A Phase II study of neoadjuvant axitinib for reducing the extent of venous tumour thrombus in clear cell renal cell cancer with venous invasion (NAXIVA)
GD Stewart, SJ Welsh, S Ursprung… - British journal of …, 2022 - nature.com
Background Surgery for renal cell carcinoma (RCC) with venous tumour thrombus (VTT)
extension into the renal vein (RV) and/or inferior vena cava (IVC) has high peri-surgical …
extension into the renal vein (RV) and/or inferior vena cava (IVC) has high peri-surgical …
[HTML][HTML] Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors
…, D Gale, A Ruiz-Valdepenas, T Klatte, S Ursprung… - Genome medicine, 2020 - Springer
Background Cell-free tumor-derived DNA (ctDNA) allows non-invasive monitoring of
cancers, but its utility in renal cell cancer (RCC) has not been established. Methods Here, a …
cancers, but its utility in renal cell cancer (RCC) has not been established. Methods Here, a …
Hyperpolarized carbon-13 MRI for early response assessment of neoadjuvant chemotherapy in breast cancer patients
Hyperpolarized carbon-13 MRI allows response assessment in patients with breast cancer
after 7–11 days of neoadjuvant chemotherapy and outperformed state-of-the-art and …
after 7–11 days of neoadjuvant chemotherapy and outperformed state-of-the-art and …
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-13C]Pyruvate Demonstrates Heterogeneity in Lactate Labeling: A Proof of …
…, AB Gill, S Deen, CJ Daniels, S Ursprung… - Radiology: Imaging …, 2022 - pubs.rsna.org
Purpose To evaluate glioblastoma (GBM) metabolism by using hyperpolarized carbon 13 (
13 C) MRI to monitor the exchange of the hyperpolarized 13 C label between injected [1- 13 C…
13 C) MRI to monitor the exchange of the hyperpolarized 13 C label between injected [1- 13 C…