User profiles for Stephan W. Grill

Stephan W Grill

Max Planck Institute of Molecular Cell Biology and Genetics
Verified email at mpi-cbg.de
Cited by 15711

Turing's next steps: the mechanochemical basis of morphogenesis

J Howard, SW Grill, JS Bois - Nature Reviews Molecular Cell Biology, 2011 - nature.com
Nearly 60 years ago, Alan Turing showed theoretically how two chemical species, termed
morphogens, diffusing and reacting with each other can generate spatial patterns. Diffusion …

Hydrodynamic theory of active matter

F Jülicher, SW Grill, G Salbreux - Reports on Progress in Physics, 2018 - iopscience.iop.org
We review the general hydrodynamic theory of active soft materials that is motivated in
particular by biological matter. We present basic concepts of irreversible thermodynamics of …

Cell polarity: mechanochemical patterning

NW Goehring, SW Grill - Trends in cell biology, 2013 - cell.com
Nearly every cell type exhibits some form of polarity, yet the molecular mechanisms vary
widely. Here we examine what we term ‘chemical systems' where cell polarization arises …

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

…, JN Bembenek, AC Reymann, R Böhme, SW Grill… - Science, 2014 - science.org
Introduction In vivo imaging provides a window into the spatially complex, rapidly evolving
physiology of the cell that structural imaging alone cannot. However, observing this …

Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

SW Grill, P GoÈnczy, EHK Stelzer, AA Hyman - Nature, 2001 - nature.com
Cell divisions that create daughter cells of different sizes are crucial for the generation of
cell diversity during animal development 1 . In such asymmetric divisions, the mitotic spindle …

The distribution of active force generators controls mitotic spindle position

SW Grill, J Howard, E Schaffer, EHK Stelzer, AA Hyman - Science, 2003 - science.org
During unequal cell divisions a mitotic spindle is eccentrically positioned before cell cleavage.
To determine the basis of the net force imbalance that causes spindle displacement in one…

[PDF][PDF] Pattern formation in active fluids

JS Bois, F Jülicher, SW Grill - Biophysical Journal, 2011 - cell.com
… Bois, Frank Jülicher, Stephan W. Grill. Motivated by the dynamics of the actomyosin cell
cortex in which stress generation is under biochemical regulation, we develop a hydrodynamic …

Phase separation of a yeast prion protein promotes cellular fitness

…, E Nüske, D Richter, W Baumeister, SW Grill… - Science, 2018 - science.org
INTRODUCTION The formation of dynamic, membraneless compartments using intracellular
phase transitions such as phase separation and gelation provides an efficient way for cells …

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

M Mayer, M Depken, JS Bois, F Jülicher, SW Grill - Nature, 2010 - nature.com
Asymmetric cell divisions are essential for the development of multicellular organisms. To
proceed, they require an initially symmetric cell to polarize 1 . In Caenorhabditis elegans …

Forces driving epithelial spreading in zebrafish gastrulation

…, R Hauschild, F Oswald, J Roensch, SW Grill… - Science, 2012 - science.org
Contractile actomyosin rings drive various fundamental morphogenetic processes ranging
from cytokinesis to wound healing. Actomyosin rings are generally thought to function by …