Background: Isolated tears of the subscapularis occur less commonly than those involving
the superior and posterior components of the rotator cuff. The purpose of the present study …

In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA
double-strand break repair induced by ionizing radiation and during V(D)J recombination in …

Members of the LAP protein family, LET-413 in Caenorhabditis elegans, Scribble in Drosophila
melanogaster and Erbin, Lano, Densin-180 and hScrib in mammals, have conserved …

Components of the evolutionarily conserved developmental planar cell polarity (PCP) pathway
were recently described to play a prominent role in cancer cell dissemination. However, …

Drosophila Scribble is implicated in the development of normal synapse structure and
epithelial tissues, but it remains unclear how it plays a role and which process it controls [1–3]. …

Disruption of the endothelial barrier by tumour-derived secreted factors is a critical step in
cancer cell extravasation and metastasis. Here, by comparative proteomic analysis of …

Functional interplay between tumour cells and their neoplastic extracellular matrix plays a
decisive role in malignant progression of carcinomas. Here we provide a comprehensive data …

Polyglutamylation is an important posttranslational modi-fication of tubulin that is very active
in nerve cells, where it accounts for the main factor responsible for tubulin het-erogeneity. In …

Controlled regulation of Rho GTPase activity is an essential component mediating growth
factor–stimulated migration. We have previously shown that angiomotin (Amot), a membrane-…

Mechanical signals from the tumor microenvironment modulate cell mechanics and influence
cell metabolism to promote cancer aggressiveness. Cells withstand external forces by …