User profiles for Stephane Peyrégne

Stéphane Peyrégne

Max Planck Institute for Evolutionary Anthropology
Verified email at eva.mpg.de
Cited by 1731

A high-coverage Neandertal genome from Vindija Cave in Croatia

…, M Hajdinjak, B Vernot, L Skov, P Hsieh, S Peyrégne… - Science, 2017 - science.org
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal from ~…

The genome of the offspring of a Neanderthal mother and a Denisovan father

…, S Grote, B Viola, M Hajdinjak, S Peyrégne… - Nature, 2018 - nature.com
Neanderthals and Denisovans are extinct groups of hominins that separated from each other
more than 390,000 years ago 1 , 2 . Here we present the genome of ‘Denisova 11’, a bone …

A high-coverage Neandertal genome from Chagyrskaya Cave

…, M Chintalapati, S Peyrégne… - Proceedings of the …, 2020 - National Acad Sciences
We sequenced the genome of a Neandertal from Chagyrskaya Cave in the Altai Mountains,
Russia, to 27-fold genomic coverage. We show that this Neandertal was a female and that …

[HTML][HTML] Genetic insights into the social organization of Neanderthals

L Skov, S Peyrégne, D Popli, LNM Iasi, T Devièse… - Nature, 2022 - nature.com
Genomic analyses of Neanderthals have previously provided insights into their population
history and relationship to modern humans 1, 2, 3, 4, 5, 6, 7, 8, but the social organization of …

Detecting ancient positive selection in humans using extended lineage sorting

S Peyrégne, MJ Boyle, M Dannemann… - Genome …, 2017 - genome.cshlp.org
Natural selection that affected modern humans early in their evolution has likely shaped some
of the traits that set present-day humans apart from their closest extinct and living relatives…

Nuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe

S Peyrégne, V Slon, F Mafessoni, C De Filippo… - Science …, 2019 - science.org
Little is known about the population history of Neandertals over the hundreds of thousands
of years of their existence. We retrieved nuclear genomic sequences from two Neandertals, …

[HTML][HTML] KIN: a method to infer relatedness from low-coverage ancient DNA

D Popli, S Peyrégne, BM Peter - Genome Biology, 2023 - Springer
Genetic kinship of ancient individuals can provide insights into their culture and social hierarchy,
and is relevant for downstream genetic analyses. However, estimating relatedness from …

[HTML][HTML] AuthentiCT: a model of ancient DNA damage to estimate the proportion of present-day DNA contamination

S Peyrégne, BM Peter - Genome biology, 2020 - Springer
Contamination from present-day DNA is a fundamental issue when studying ancient DNA
from historical or archaeological material, and quantifying the amount of contamination is …

A genetic analysis of the Gibraltar Neanderthals

…, M Hajdinjak, S Peyrégne… - Proceedings of the …, 2019 - National Acad Sciences
The Forbes’ Quarry and Devil’s Tower partial crania from Gibraltar are among the first Neanderthal
remains ever found. Here, we show that small amounts of ancient DNA are preserved …

Present‐Day DNA Contamination in Ancient DNA Datasets

S Peyrégne, K Prüfer - BioEssays, 2020 - Wiley Online Library
Present‐day contamination can lead to false conclusions in ancient DNA studies. A number
of methods are available to estimate contamination, which use a variety of signals and are …