Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report
…, SP McGuinness, BJ McVerry, SK Montgomery… - Medrxiv, 2021 - medrxiv.org
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
[HTML][HTML] Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
…, A Schäfer, J Won, AJ Brown, SA Montgomery… - Nature …, 2020 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a
severe respiratory disease associated with more than 2468 human infections and over 851 …
severe respiratory disease associated with more than 2468 human infections and over 851 …
[HTML][HTML] A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
…, A Schäfer, CE Edwards, DR Martinez, SA Montgomery… - Nature, 2020 - nature.com
Coronaviruses are prone to transmission to new host species, as recently demonstrated by
the spread to humans of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
the spread to humans of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
…, AS George, CS Hill, SA Montgomery… - Science translational …, 2020 - science.org
Coronaviruses (CoVs) traffic frequently between species resulting in novel disease outbreaks,
most recently exemplified by the newly emerged SARS-CoV-2, the causative agent of …
most recently exemplified by the newly emerged SARS-CoV-2, the causative agent of …
[PDF][PDF] A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
…, RC Boucher, LE Gralinski, SA Montgomery… - Cell, 2020 - cell.com
The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …
A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner
DR Donohoe, D Holley, LB Collins, SA Montgomery… - Cancer discovery, 2014 - AACR
Whether dietary fiber protects against colorectal cancer is controversial because of conflicting
results from human epidemiologic studies. However, these studies and mouse models of …
results from human epidemiologic studies. However, these studies and mouse models of …
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
…, D Weissman, BF Haynes, SA Montgomery… - Science, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies …
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies …
[PDF][PDF] Antitumor responses in the absence of toxicity in solid tumors by targeting B7-H3 via chimeric antigen receptor T cells
H Du, K Hirabayashi, S Ahn, NP Kren, SA Montgomery… - Cancer cell, 2019 - cell.com
The high expression across multiple tumor types and restricted expression in normal tissues
make B7-H3 an attractive target for immunotherapy. We generated chimeric antigen …
make B7-H3 an attractive target for immunotherapy. We generated chimeric antigen …
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice
…, MA Seibold, WK O'Neal, SA Montgomery… - Science translational …, 2022 - science.org
A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC)…
post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC)…
[HTML][HTML] A mouse model of chikungunya virus–induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence
TE Morrison, L Oko, SA Montgomery… - The American journal of …, 2011 - Elsevier
Chikungunya virus (CHIKV), an emerging mosquito-borne Alphavirus, causes debilitating
rheumatic disease in humans that can last for weeks to months. Starting in 2004, a CHIKV …
rheumatic disease in humans that can last for weeks to months. Starting in 2004, a CHIKV …