[PDF][PDF] Mutant IDH1 promotes glioma formation in vivo
…, JP Robinson, GL Robinson, AE Welker, SN Angel… - Cell reports, 2018 - cell.com
Isocitrate dehydrogenase 1 (IDH1) is the most commonly mutated gene in grade II–III glioma
and secondary glioblastoma (GBM). A causal role for IDH1 R132H in gliomagenesis has …
and secondary glioblastoma (GBM). A causal role for IDH1 R132H in gliomagenesis has …
AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis
…, MR Silvis, GL Parkman, GM Fischer, SN Angel… - Molecular Cancer …, 2019 - AACR
This study suggests that AKT1 E17K promotes melanoma brain metastasis through activation
of FAK and provides a rationale for the therapeutic targeting of AKT and/or FAK to reduce …
of FAK and provides a rationale for the therapeutic targeting of AKT and/or FAK to reduce …
[HTML][HTML] FDG PET/CT to detect bone marrow involvement in the initial staging of patients with aggressive non-Hodgkin lymphoma: results from the prospective …
D Kaddu-Mulindwa, B Altmann, G Held, S Angel… - European journal of …, 2021 - Springer
Purpose Fluorine-18 fluorodeoxyglucose positron emission tomography combined with
computed tomography (FDG PET/CT) is the standard for staging aggressive non-Hodgkin …
computed tomography (FDG PET/CT) is the standard for staging aggressive non-Hodgkin …
Toward optimal cryopreservation and storage for achievement of high cell recovery and maintenance of cell viability and T cell functionality
S Angel, H von Briesen, YJ Oh, MK Baller… - Biopreservation and …, 2016 - liebertpub.com
Cryopreservation of biological materials such as cells, tissues, and organs is a prevailing
topic of high importance. It is employed not only in many research fields but also in the clinical …
topic of high importance. It is employed not only in many research fields but also in the clinical …
[HTML][HTML] Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly
S Amiar, ML Husby, KJ Wijesinghe, S Angel… - Journal of Biological …, 2021 - ASBMB
Marburg virus (MARV) is a lipid-enveloped virus harboring a negative-sense RNA genome,
which has caused sporadic outbreaks of viral hemorrhagic fever in sub-Saharan Africa. …
which has caused sporadic outbreaks of viral hemorrhagic fever in sub-Saharan Africa. …
[HTML][HTML] Landscape of 4D cell interaction in Hodgkin and non-Hodgkin lymphomas
…, E Donnadieu, N Flinner, V Poeschel, S Angel… - Cancers, 2021 - mdpi.com
Simple Summary Little is known about the motility and interaction of primary human lymphoma
cells in lymph nodes. The aim of this study therefore was to analyze for the first time if …
cells in lymph nodes. The aim of this study therefore was to analyze for the first time if …
[HTML][HTML] Prolonged remissions after nivolumab plus gemcitabine/oxaliplatin in relapsed/refractory T-cell lymphoma
R Houot, V Poeschel, B Altmann, S Angel… - …, 2022 - journals.lww.com
Peripheral T-cell lymphomas (PTCL) represent a hetero-geneous group of aggressive
lymphomas, which usually carry a poor prognosis. Malignant T cells may overexpress …
lymphomas, which usually carry a poor prognosis. Malignant T cells may overexpress …
Contribution of the Golgi apparatus in morphogenesis of a virus-induced cytopathic vacuolar system
R Sengupta, EM Mihelc, S Angel… - Life Science …, 2022 - life-science-alliance.org
The Golgi apparatus (GA) in mammalian cells is pericentrosomally anchored and exhibits a
stacked architecture. During infections by members of the alphavirus genus, the host cell GA …
stacked architecture. During infections by members of the alphavirus genus, the host cell GA …
The CryoAPEX method for electron microscopy analysis of membrane protein localization within ultrastructurally-preserved cells
EM Mihelc, S Angel, RV Stahelin, S Mattoo - JoVE (Journal of Visualized …, 2020 - jove.com
Key cellular events like signal transduction and membrane trafficking rely on proper protein
location within cellular compartments. Understanding precise subcellular localization of …
location within cellular compartments. Understanding precise subcellular localization of …
[HTML][HTML] Role of FDG PET/CT to detect bone marrow involvement in the initial staging of aggressive non-Hodgkin lymphoma
…, G Held, M Ziepert, K Menhart, J Grosse, S Angel… - Blood, 2019 - Elsevier
BACKGROUND: According to the Lugano classification (Cheson et al., JCO 2014, 32: 3059-3067)
fludeoxyglucose positron emission tomography combined with computed tomography …
fludeoxyglucose positron emission tomography combined with computed tomography …