User profiles for Stephanie Halford
Stephanie HalfordUniversity of Oxford Verified email at eye.ox.ac.uk Cited by 5985 |
Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6. 2 (KCNJ11) and SUR1 (ABCC8) confirm that the …
The genes ABCC8 and KCNJ11, which encode the subunits sulfonylurea receptor 1 (SUR1)
and inwardly rectifying potassium channel (Kir6.2) of the β-cell ATP-sensitive potassium (K …
and inwardly rectifying potassium channel (Kir6.2) of the β-cell ATP-sensitive potassium (K …
The evolution of irradiance detection: melanopsin and the non-visual opsins
SN Peirson, S Halford… - … Transactions of the …, 2009 - royalsocietypublishing.org
Circadian rhythms are endogenous 24 h cycles that persist in the absence of external time
cues. These rhythms provide an internal representation of day length and optimize physiology …
cues. These rhythms provide an internal representation of day length and optimize physiology …
[PDF][PDF] VA opsin-based photoreceptors in the hypothalamus of birds
S Halford, SS Pires, M Turton, L Zheng… - Current Biology, 2009 - cell.com
Studies in the 1930s demonstrated that birds possess photoreceptors that are located within
the hypothalamus and regulate photoperiodic responses to day length [1, 2]. Most recently, …
the hypothalamus and regulate photoperiodic responses to day length [1, 2]. Most recently, …
Targeted Mutagenesis of the Hira Gene Results in Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives Prior to Early Embryonic …
…, H Farmer, W Kimber, S Halford… - … and cellular biology, 2002 - Taylor & Francis
The Hira gene encodes a nuclear WD40 domain protein homologous to the yeast transcriptional
corepressors Hir1p and Hir2p. Using targeted mutagenesis we demonstrate that Hira is …
corepressors Hir1p and Hir2p. Using targeted mutagenesis we demonstrate that Hira is …
Functional diversity of melanopsins and their global expression in the teleost retina
Melanopsin (OPN4) is an opsin photopigment that, in mammals, confers photosensitivity to
retinal ganglion cells and regulates circadian entrainment and pupil constriction. In non-…
retinal ganglion cells and regulates circadian entrainment and pupil constriction. In non-…
Large-Scale Analysis of the Relationship between CYP11A Promoter Variation, Polycystic Ovarian Syndrome, and Serum Testosterone
…, S Taponen, AL Hartikainen, S Halford… - The Journal of …, 2004 - academic.oup.com
CYP11A, the gene encoding P450scc, a key enzyme in steroid biosynthesis, is a strong
biological candidate for polycystic ovary syndrome (PCOS) susceptibility. Four of the five …
biological candidate for polycystic ovary syndrome (PCOS) susceptibility. Four of the five …
Unravelling the genetics of inherited retinal dystrophies: Past, present and future
The identification of the genes underlying monogenic diseases has been of interest to
clinicians and scientists for many years. Using inherited retinal dystrophies as an example of …
clinicians and scientists for many years. Using inherited retinal dystrophies as an example of …
Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina
…, RG Foster, MW Hankins, S Halford - Journal of …, 2009 - Soc Neuroscience
Melanopsin is the photopigment that confers photosensitivity to a subset of retinal ganglion
cells (pRGCs) that regulate many non-image-forming tasks such as the detection of light for …
cells (pRGCs) that regulate many non-image-forming tasks such as the detection of light for …
Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43
S Halford, MS Freedman, J Bellingham, SL Inglis… - Genomics, 2001 - Elsevier
As part of an ongoing search to identify novel mammalian photopigments that may mediate
nonvisual tasks such as circadian entrainment and acute suppression of pineal melatonin …
nonvisual tasks such as circadian entrainment and acute suppression of pineal melatonin …
Detailed phenotypic and genotypic characterization of bietti crystalline dystrophy
… Author links open overlay panel Stephanie Halford PhD 1 ∗∗ , Gerald Liew PhD 2 3 ∗∗ ,
Donna S. Mackay PhD 3 , Panagiotis I. Sergouniotis PhD 3 4 , Richard Holt DPhil 1 , Suzanne …
Donna S. Mackay PhD 3 , Panagiotis I. Sergouniotis PhD 3 4 , Richard Holt DPhil 1 , Suzanne …