Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic
reprogramming is induced by the concerted activation/repression of transcription factors and …

Rickettsia conorii, a strictly intracellular and category C priority bacterial pathogen (NIAID),
invades different mammalian cells. Although some signaling events involved in bacterial entry …

Listeria monocytogenes uptake by nonphagocytic cells is promoted by the bacterial invasion
proteins internalin and InlB, which bind to their host receptors E-cadherin and hepatocyte …

In response to chemoattractants neutrophils extend an actin-rich pseudopod, which imparts
morphological polarity and is required for migration. Even when stimulated by an isotropic …

The facultative intracellular bacterial pathogen Listeria monocytogenes has evolved multiple
strategies to invade a large panel of mammalian cells. Host cell invasion is critical for …

On treatment with chemoattractant, the neutrophil plasma membrane becomes organized
into detergent-resistant membrane domains (DRMs), the distribution of which is intimately …

Intracellular pathogens have evolved diverse strategies to invade and survive within host
cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is …

Objective Primary human trophoblasts were previously shown to be resistant to viral
infection, and able to confer this resistance to nontrophoblast cells. Can trophoblasts protect …

Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health
concern, and new treatment strategies are needed. Targeting inflammatory innate immunity …

The cholesterol-dependent cytolysins (CDCs) are a large family of pore-forming toxins that
are produced by numerous Gram-positive bacterial pathogens. These toxins are released in …