User profiles for Stephanie Seveau
Stephanie SeveauAssociate Professor Verified email at osu.edu Cited by 2943 |
Histone modifications induced by a family of bacterial toxins
Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic
reprogramming is induced by the concerted activation/repression of transcription factors and …
reprogramming is induced by the concerted activation/repression of transcription factors and …
[HTML][HTML] Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii
Rickettsia conorii, a strictly intracellular and category C priority bacterial pathogen (NIAID),
invades different mammalian cells. Although some signaling events involved in bacterial entry …
invades different mammalian cells. Although some signaling events involved in bacterial entry …
Role of lipid rafts in E-cadherin– and HGF-R/Met–mediated entry of Listeria monocytogenes into host cells
Listeria monocytogenes uptake by nonphagocytic cells is promoted by the bacterial invasion
proteins internalin and InlB, which bind to their host receptors E-cadherin and hepatocyte …
proteins internalin and InlB, which bind to their host receptors E-cadherin and hepatocyte …
[HTML][HTML] Membrane lipid organization is critical for human neutrophil polarization
LM Pierini, RJ Eddy, M Fuortes, S Seveau… - Journal of Biological …, 2003 - ASBMB
In response to chemoattractants neutrophils extend an actin-rich pseudopod, which imparts
morphological polarity and is required for migration. Even when stimulated by an isotropic …
morphological polarity and is required for migration. Even when stimulated by an isotropic …
[HTML][HTML] Molecular mechanisms exploited by Listeria monocytogenes during host cell invasion
S Seveau, J Pizarro-Cerda, P Cossart - Microbes and Infection, 2007 - Elsevier
The facultative intracellular bacterial pathogen Listeria monocytogenes has evolved multiple
strategies to invade a large panel of mammalian cells. Host cell invasion is critical for …
strategies to invade a large panel of mammalian cells. Host cell invasion is critical for …
Cytoskeleton-dependent membrane domain segregation during neutrophil polarization
S Seveau, RJ Eddy, FR Maxfield… - Molecular biology of the …, 2001 - Am Soc Cell Biol
On treatment with chemoattractant, the neutrophil plasma membrane becomes organized
into detergent-resistant membrane domains (DRMs), the distribution of which is intimately …
into detergent-resistant membrane domains (DRMs), the distribution of which is intimately …
[HTML][HTML] The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes
…, EM Wilson-Kubalek, RK Tweten, S Seveau - PLoS …, 2011 - journals.plos.org
Intracellular pathogens have evolved diverse strategies to invade and survive within host
cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is …
cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is …
Human trophoblasts confer resistance to viruses implicated in perinatal infection
…, PR Kinchington, S Vadia, S Seveau… - American journal of …, 2015 - Elsevier
Objective Primary human trophoblasts were previously shown to be resistant to viral
infection, and able to confer this resistance to nontrophoblast cells. Can trophoblasts protect …
infection, and able to confer this resistance to nontrophoblast cells. Can trophoblasts protect …
Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis
…, L Hall-Stoodley, S Seveau… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health
concern, and new treatment strategies are needed. Targeting inflammatory innate immunity …
concern, and new treatment strategies are needed. Targeting inflammatory innate immunity …
Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes
S Seveau - MACPF/CDC Proteins-Agents of Defence, Attack and …, 2014 - Springer
The cholesterol-dependent cytolysins (CDCs) are a large family of pore-forming toxins that
are produced by numerous Gram-positive bacterial pathogens. These toxins are released in …
are produced by numerous Gram-positive bacterial pathogens. These toxins are released in …