User profiles for Stephen Chelko
 | Stephen ChelkoFlorida State University, College of Medicine Verified email at med.fsu.edu Cited by 1393 |
Retracted and republished: A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy
Aims Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by
ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a …
ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a …
[HTML][HTML] Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy
SP Chelko, A Asimaki, P Andersen, D Bedja… - JCI insight, 2016 - ncbi.nlm.nih.gov
Arrhythmogenic cardiomyopathy (ACM) is characterized by redistribution of junctional proteins,
arrhythmias, and progressive myocardial injury. We previously reported that SB216763 (…
arrhythmias, and progressive myocardial injury. We previously reported that SB216763 (…
Sudden cardiac death prediction in arrhythmogenic right ventricular cardiomyopathy: a multinational collaboration
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with
ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently …
ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently …
Therapeutic modulation of the immune response in arrhythmogenic cardiomyopathy
SP Chelko, A Asimaki, J Lowenthal, C Bueno-Beti… - Circulation, 2019 - Am Heart Assoc
Background: Inflammation is a prominent feature of arrhythmogenic cardiomyopathy (ACM),
but whether it contributes to the disease phenotype is not known. Methods: To define the …
but whether it contributes to the disease phenotype is not known. Methods: To define the …
[HTML][HTML] Precardiac organoids form two heart fields via Bmp/Wnt signaling
The discovery of the first heart field (FHF) and the second heart field (SHF) led us to understand
how cardiac lineages and structures arise during development. However, it remains …
how cardiac lineages and structures arise during development. However, it remains …
[PDF][PDF] Neonatal transplantation confers maturation of PSC-derived cardiomyocytes conducive to modeling cardiomyopathy
Pluripotent stem cells (PSCs) offer unprecedented opportunities for disease modeling and
personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and …
personalized medicine. However, PSC-derived cells exhibit fetal-like characteristics and …
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy
Myocyte death occurs in many inherited and acquired cardiomyopathies, including
arrhythmogenic cardiomyopathy (ACM), a genetic heart disease plagued by the prevalence of …
arrhythmogenic cardiomyopathy (ACM), a genetic heart disease plagued by the prevalence of …
A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy
Aims Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized
by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a …
by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a …
[HTML][HTML] Mutations in Alström protein impair terminal differentiation of cardiomyocytes
…, R Yonescu, DAS Batista, Y Chen, S Chelko… - Nature …, 2014 - nature.com
Cardiomyocyte cell division and replication in mammals proceed through embryonic development
and abruptly decline soon after birth. The process governing cardiomyocyte cell cycle …
and abruptly decline soon after birth. The process governing cardiomyocyte cell cycle …
Arrhythmogenic right ventricular cardiomyopathy presenting as clinical myocarditis in women
Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) classically initially
present with ventricular arrhythmias or, less commonly, heart failure. Myocardial inflammation …
present with ventricular arrhythmias or, less commonly, heart failure. Myocardial inflammation …