User profiles for Stephen J. DeCamp
Stephen J. DeCampResearch Associate, Harvard University Verified email at hsph.harvard.edu Cited by 3524 |
Spontaneous motion in hierarchically assembled active matter
With remarkable precision and reproducibility, cells orchestrate the cooperative action of
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much larger …
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much larger …
Topology and dynamics of active nematic vesicles
Engineering synthetic materials that mimic the remarkable complexity of living organisms is
a fundamental challenge in science and technology. We studied the spatiotemporal patterns …
a fundamental challenge in science and technology. We studied the spatiotemporal patterns …
Orientational order of motile defects in active nematics
The study of liquid crystals at equilibrium has led to fundamental insights into the nature of
ordered materials, as well as to practical applications such as display technologies. Active …
ordered materials, as well as to practical applications such as display technologies. Active …
Transition from turbulent to coherent flows in confined three-dimensional active fluids
INTRODUCTION Conventional nonequilibrium systems are composed of inanimate components
whose dynamics is powered by the external input of energy. For example, in a turbulent …
whose dynamics is powered by the external input of energy. For example, in a turbulent …
Geometric constraints during epithelial jamming
As an injury heals, an embryo develops or a carcinoma spreads, epithelial cells systematically
change their shape. In each of these processes cell shape is studied extensively whereas …
change their shape. In each of these processes cell shape is studied extensively whereas …
[HTML][HTML] In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …
Tunable dynamics of microtubule-based active isotropic gels
We investigate the dynamics of an active gel of bundled microtubules (MTs) that is driven by
clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of …
clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of …
Statistical properties of autonomous flows in 2D active nematics
We study the dynamics of a tunable 2D active nematic liquid crystal composed of microtubules
and kinesin motors confined to an oil–water interface. Kinesin motors continuously inject …
and kinesin motors confined to an oil–water interface. Kinesin motors continuously inject …
[HTML][HTML] Epithelial layer unjamming shifts energy metabolism toward glycolysis
SJ DeCamp, VMK Tsuda, J Ferruzzi, SA Koehler… - Scientific Reports, 2020 - nature.com
In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite
event is collective epithelial cellular migration. For example, cells at the advancing front of a …
event is collective epithelial cellular migration. For example, cells at the advancing front of a …
Multiscale microtubule dynamics in active nematics
In microtubule-based active nematics, motor-driven extensile motion of microtubule bundles
powers chaotic large-scale dynamics. We quantify the interfilament sliding motion both in …
powers chaotic large-scale dynamics. We quantify the interfilament sliding motion both in …