User profiles for Stephen J. DeCamp

Stephen J. DeCamp

Research Associate, Harvard University
Verified email at hsph.harvard.edu
Cited by 3524

Spontaneous motion in hierarchically assembled active matter

T Sanchez, DTN Chen, SJ DeCamp, M Heymann… - Nature, 2012 - nature.com
With remarkable precision and reproducibility, cells orchestrate the cooperative action of
thousands of nanometre-sized molecular motors to carry out mechanical tasks at much larger …

Topology and dynamics of active nematic vesicles

FC Keber, E Loiseau, T Sanchez, SJ DeCamp, L Giomi… - Science, 2014 - science.org
Engineering synthetic materials that mimic the remarkable complexity of living organisms is
a fundamental challenge in science and technology. We studied the spatiotemporal patterns …

Orientational order of motile defects in active nematics

SJ DeCamp, GS Redner, A Baskaran, MF Hagan… - Nature materials, 2015 - nature.com
The study of liquid crystals at equilibrium has led to fundamental insights into the nature of
ordered materials, as well as to practical applications such as display technologies. Active …

Transition from turbulent to coherent flows in confined three-dimensional active fluids

KT Wu, JB Hishamunda, DTN Chen, SJ DeCamp… - Science, 2017 - science.org
INTRODUCTION Conventional nonequilibrium systems are composed of inanimate components
whose dynamics is powered by the external input of energy. For example, in a turbulent …

Geometric constraints during epithelial jamming

…, JA Mitchel, B Gweon, S A. Koehler, SJ DeCamp… - Nature physics, 2018 - nature.com
As an injury heals, an embryo develops or a carcinoma spreads, epithelial cells systematically
change their shape. In each of these processes cell shape is studied extensively whereas …

[HTML][HTML] In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition

…, A Das, MJ O'Sullivan, IT Stancil, SJ DeCamp… - Nature …, 2020 - nature.com
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

Tunable dynamics of microtubule-based active isotropic gels

G Henkin, SJ DeCamp, DTN Chen… - … of the Royal …, 2014 - royalsocietypublishing.org
We investigate the dynamics of an active gel of bundled microtubules (MTs) that is driven by
clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of …

Statistical properties of autonomous flows in 2D active nematics

LM Lemma, SJ DeCamp, Z You, L Giomi, Z Dogic - Soft matter, 2019 - pubs.rsc.org
We study the dynamics of a tunable 2D active nematic liquid crystal composed of microtubules
and kinesin motors confined to an oil–water interface. Kinesin motors continuously inject …

[HTML][HTML] Epithelial layer unjamming shifts energy metabolism toward glycolysis

SJ DeCamp, VMK Tsuda, J Ferruzzi, SA Koehler… - Scientific Reports, 2020 - nature.com
In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite
event is collective epithelial cellular migration. For example, cells at the advancing front of a …

Multiscale microtubule dynamics in active nematics

LM Lemma, MM Norton, AM Tayar, SJ DeCamp… - Physical review …, 2021 - APS
In microtubule-based active nematics, motor-driven extensile motion of microtubule bundles
powers chaotic large-scale dynamics. We quantify the interfilament sliding motion both in …