User profiles for Stephen J. Eglen

Stephen J. Eglen

Cambridge University
Verified email at cam.ac.uk
Cited by 3392

Development of retinal ganglion cell structure and function

E Sernagor, SJ Eglen, ROL Wong - Progress in retinal and eye research, 2001 - Elsevier
In this review, we summarize the main stages of structural and functional development of
retinal ganglion cells (RGCs). We first consider the various mechanisms that are involved in …

Detecting pairwise correlations in spike trains: an objective comparison of methods and application to the study of retinal waves

CS Cutts, SJ Eglen - Journal of Neuroscience, 2014 - Soc Neuroscience
Correlations in neuronal spike times are thought to be key to processing in many neural
systems. Many measures have been proposed to summarize these correlations and of these the …

Developmental loss of synchronous spontaneous activity in the mouse retina is independent of visual experience

J Demas, SJ Eglen, ROL Wong - Journal of Neuroscience, 2003 - Soc Neuroscience
In the immature retina, correlated spontaneous activity in the form of propagating waves is
thought to be necessary for the refinement of connections between the retina and its targets. …

[HTML][HTML] Ten simple rules for taking advantage of Git and GitHub

…, C Fufezan, T Ternent, SJ Eglen… - PLoS computational …, 2016 - journals.plos.org
Bioinformatics is a broad discipline in which one common denominator is the need to produce
and/or use software that can be applied to biological data in different contexts. To enable …

Following the ontogeny of retinal waves: Pan‐retinal recordings of population dynamics in the neonatal mouse

…, J van Coppenhagen, SJ Eglen… - The Journal of …, 2014 - Wiley Online Library
Key points Novel pan‐retinal recordings of mouse retinal waves were obtained at near
cellular resolution using a large‐scale, high‐density array of 4096 electrodes to investigate …

Toward standard practices for sharing computer code and programs in neuroscience

SJ Eglen, B Marwick, YO Halchenko, M Hanke… - Nature …, 2017 - nature.com
Computational techniques are central in many areas of neuroscience and are relatively easy
to share. This paper describes why computer programs underlying scientific publications …

[HTML][HTML] Ten simple rules for writing Dockerfiles for reproducible data science

D Nüst, V Sochat, B Marwick, SJ Eglen… - PLoS computational …, 2020 - journals.plos.org
Computational science has been greatly improved by the use of containers for packaging
software and data dependencies. In a scholarly context, the main drivers for using these …

[HTML][HTML] Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures

…, FE Kapucu, L Aarnos, A Vinogradov, SJ Eglen… - Scientific reports, 2019 - nature.com
Human pluripotent stem cell (hPSC)-derived neurons provide exciting opportunities for in
vitro modeling of neurological diseases and for advancing drug development and …

[HTML][HTML] A comparison of computational methods for detecting bursts in neuronal spike trains and their application to human stem cell-derived neuronal networks

…, CW Thomas, O Paulsen, SJ Eglen - Journal of …, 2016 - journals.physiology.org
Accurate identification of bursting activity is an essential element in the characterization of
neuronal network activity. Despite this, no one technique for identifying bursts in spike trains …

Characterization of early cortical neural network development in multiwell microelectrode array plates

…, K Wallace, WR Mundy, SJ Eglen… - Journal of …, 2016 - journals.sagepub.com
We examined neural network ontogeny using microelectrode array (MEA) recordings made
in multiwell MEA (mwMEA) plates over the first 12 days in vitro (DIV). In primary cortical …