The small intestine mediates the absorption of amino acids after ingestion of protein and
sustains the supply of amino acids to all tissues. The small intestine is an important contributor …

The brush-border membrane of the small intestine and kidney proximal tubule are the major
sites for the absorption and re-absorption of nutrients in the body respectively. Transport of …

Apicomplexans are obligate intracellular parasites that scavenge essential nutrients from their
hosts via transporter proteins on their plasma membrane. The identities of the transporters …

Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC)
permeases serve as the primary import pathway for many micronutrients including the first-row …

… Kiran Javed, Stephen J. Fairweather; Amino acid transporters in the regulation of insulin
secretion and signalling. Biochem Soc Trans 30 April 2019; 47 (2): 571–590. doi: https://doi.org/…

Solute carriers form one of three major superfamilies of membrane transporters in humans,
and include uniporters, exchangers and symporters. Following several decades of molecular …

Many solute carrier 6 (SLC6) family transporters require ancillary subunits to modify their
expression and activity. The main apical membrane neutral amino acid transporters in mouse …

Amino acid transporters play a vital role in metabolism and nutrient signaling pathways.
Typically, transport activity is investigated using single substrates and competing amounts of …

Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged
from their host cells, either through direct uptake or degradation of host proteins. Here, we …

Amino acid antiporters mediate the 1:1 exchange of groups of amino acids. Whether substrate
specificity can be different for the inward and outward facing conformation has not been …