MyoD is a master regulatory gene for myogenesis. Under the control of a retroviral long
terminal repeat, MyoD was expressed in a variety of differentiated cell types by using either a …

Expression of a complementary DNA (cDNA) encoding the mouse MyoD1 protein in a variety
of fibroblast and adipoblast cell lines converts them to myogenic cells. Polyclonal antisera …

The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4
have critical roles in skeletal muscle development. Together with the Mef2 proteins and E …

To understand gene expression changes mediated by a polyglutamine repeat expansion in
the human huntingtin protein, we used oligonucleotide DNA arrays to profile ~6000 striatal …

The expression of Myod is sufficient to convert a fibroblast to a skeletal muscle cell, and, as
such, is a model system in developmental biology for studying how a single initiating event …

Facioscapulohumeral muscular dystrophy (FSHD) is a common form of muscular dystrophy
in adults that is foremost characterized by progressive wasting of muscles in the upper body. …

Facioscapulohumeral dystrophy (FSHD) is characterized by chromatin relaxation of the D4Z4
macrosatellite array on chromosome 4 and expression of the D4Z4-encoded DUX4 gene …

To better understand transcriptional regulation during human oogenesis and preimplantation
development, we defined stage-specific transcription, which highlighted the cleavage …

Basic helix-loop-helix (bHLH) transcription factors are known to function during mammalian
neurogenesis. Here we show that transient transfection of vectors expressing neuroD2, …

Recent studies have demonstrated that MyoD initiates a feed-forward regulation of skeletal
muscle gene expression, predicting that MyoD binds directly to many genes expressed …