Infection with the free-living amoeba Naegleria fowleri leads to life-threatening primary amoebic
meningoencephalitis. Efficacious treatment options for these infections are limited, and …

Human African trypanosomiasis is a disease of sub-Saharan Africa, where millions are at risk
for the illness. The disease, commonly referred to as African sleeping sickness, is caused …

Plasmodium falciparum , the deadliest species of malaria parasites, is dependent on glycolysis
for the generation of ATP during the pathogenic red blood cell stage. Hexokinase (HK) …

Kinetoplastid‐based infections are neglected diseases that represent a significant human
health issue. Chemotherapeutic options are limited due to toxicity, parasite susceptibility, and …

A sulfonamidebenzamide series was assessed for anti-kinetoplastid parasite activity based
on structural similarity to the antiparasitic drug, nifurtimox. Through structure-activity …

Objectives: We investigated whether maternal plasma levels of the placental hormone
corticotropin-releasing hormone are elevated in pregnancies complicated by preterm labor. Study …

Cat-scratch disease affects an estimated 22,000 people in the United States each year, more
than half of whom are children or adolescents [1]. It is caused by Bartonella henselae, a …

Environmentally transformative human use of land accelerated with the emergence of
agriculture, but the extent, trajectory, and implications of these early changes are not well …

OBJECTIVE: The purpose of this study was to determine the incidence and types of genitourinary
complications in pediatric patients with Crohn's disease. CONCLUSION: Genitourinary …

Purpose: We investigated the response to antiepileptic drug (AED) therapy in patients with
localisation‐related epilepsy associated with different underlying causes. Methods: Five …