EB1 is an evolutionarily conserved protein that localizes to the plus ends of growing
microtubules. In yeast, the EB1 homologue (BIM1) has been shown to modulate microtubule …

Cell migration occurs through the protrusion of the actin-enriched lamella. Here, we investigated
the effects of RNAi depletion of ∼90 proteins implicated in actin function on lamella …

During anaphase identical sister chromatids separate and move towards opposite poles of
the mitotic spindle 1 , 2 . In the spindle, kinetochore microtubules 3 have their plus ends …

Restricting centriole duplication to once per cell cycle is critical for chromosome segregation
and genomic stability, but the mechanisms underlying this block to reduplication are unclear…

Bacterial biofilms are associated with secondary gold grains from two sites in Australia. 16S
ribosomal DNA clones of the genus Ralstonia that bear 99% similarity to the bacterium …

Cytoskeleton-associated motor proteins typically drive organelle movements in eukaryotic
cells in a manner that is tightly regulated, both spatially and temporally. In the past year, a …

EB1 is a member of a conserved protein family that localizes to growing microtubule plus
ends. EB1 proteins also recruit cell polarity and signaling molecules to microtubule tips. …

Members of the Rho/Rac/Cdc42 superfamily of GTPases [1,2] and their upstream activators,
guanine nucleotide exchange factors (GEFs) [3], have emerged as key regulators of actin …

Melanophores offer an outstanding system for the study of intracellular motility. These cells
aggregate their pigment-filled melanosomes to the cell center or disperse them throughout …

Cultured Drosophila cell lines have become an increasingly popular model system for cell
biological and functional genomic studies. One of the most commonly used lines, S2 cells, is …