User profiles for Stephen L. Wang
 | Stephen Lee WangMD-PhD Candidate, Case Western Reserve University Verified email at case.edu Cited by 426 |
[HTML][HTML] Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase
…, SL Wang, S Jaime-Figueroa, A Harbin, J Wang… - Nature …, 2019 - nature.com
PROteolysis-TArgeting Chimeras (PROTACs) are hetero-bifunctional molecules that recruit
an E3 ubiquitin ligase to a given substrate protein resulting in its targeted degradation. Many …
an E3 ubiquitin ligase to a given substrate protein resulting in its targeted degradation. Many …
Computational modeling of blood flow in the TrapEase inferior vena cava filter
MA Singer, WD Henshaw, SL Wang - Journal of Vascular and …, 2009 - Elsevier
PURPOSE: To evaluate the hemodynamics of the TrapEase vena cava filter (Cordis, Miami
Lakes, Florida) by using three-dimensional computational fluid dynamics, including …
Lakes, Florida) by using three-dimensional computational fluid dynamics, including …
Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic …
Purpose Epigenetic aberrations have been reported in hepatocellular carcinoma (HCC). In
this study of patients with unresectable HCC and chronic liver disease, epigenetic therapy …
this study of patients with unresectable HCC and chronic liver disease, epigenetic therapy …
Tisssue responses in corticotomy-and osteotomy-assisted tooth movements in rats: histology and immunostaining
L Wang, W Lee, D Lei, Y Liu, DD Yamashita… - American Journal of …, 2009 - Elsevier
INTRODUCTION: The purpose of this histologic study was to examine underlying cellular
responses to corticotomy- and osteotomy-assisted tooth movements. METHODS: Thirty-six rats …
responses to corticotomy- and osteotomy-assisted tooth movements. METHODS: Thirty-six rats …
[HTML][HTML] The CloudSat mission and the A-Train: A new dimension of space-based observations of clouds and precipitation
GL Stephens, DG Vane, RJ Boain… - Bulletin of the …, 2002 - journals.ametsoc.org
CloudSat is a satellite experiment designed to measure the vertical structure of clouds from
space. The expected launch of CloudSat is planned for 2004, and once launched, CloudSat …
space. The expected launch of CloudSat is planned for 2004, and once launched, CloudSat …
Self-Amplified HF Release and Polymer Deconstruction Cascades Triggered by Mechanical Force
Hydrogen fluoride (HF) is a versatile reagent for material transformation, with applications in
self-immolative polymers, remodeled siloxanes, and degradable polymers. The responsive …
self-immolative polymers, remodeled siloxanes, and degradable polymers. The responsive …
[HTML][HTML] The Amino Terminus of Apolipoprotein B Is Necessary but Not Sufficient for Microsomal Triglyceride Transfer Protein Responsiveness (∗)
DG Gretch, SL Sturley, L Wang, BA Lipton… - Journal of Biological …, 1996 - ASBMB
Human apolipoprotein (apo) B mediates the formation of neutral lipid-containing lipoproteins
in the liver and intestine. The association of apoB with lipid is thought to be promoted by the …
in the liver and intestine. The association of apoB with lipid is thought to be promoted by the …
The influence of fines on the hydro-mechanical behavior of sand for sustainable compacted liner and sub-base construction applications
…, IC Onuoha, II Obianyo, LU Stephen… - Asian Journal of Civil …, 2024 - Springer
The hydro-mechanical behavior of a material is an imminent criterion for assessing the
performance of a liner and sub-base material. Several materials have been explored in the past …
performance of a liner and sub-base material. Several materials have been explored in the past …
bcl-2 and p53 Oncoprotein Expression during Colorectal Tumorigenesis
FA Sinicrope, SB Ruan, KR Cleary, LC Stephens… - Cancer research, 1995 - AACR
Apoptosis or programmed cell death represents a mechanism by which cells possessing
DNA damage can be deleted. The bcl-2 proto-oncogene is a known inhibitor of apoptosis that …
DNA damage can be deleted. The bcl-2 proto-oncogene is a known inhibitor of apoptosis that …
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
…, JA Morris, G Barcenas-Morales, A Fischer, L Stephens… - Science, 2013 - science.org
Genetic mutations cause primary immunodeficiencies (PIDs) that predispose to infections.
Here, we describe activated PI3K-δ syndrome (APDS), a PID associated with a dominant gain-…
Here, we describe activated PI3K-δ syndrome (APDS), a PID associated with a dominant gain-…