Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

Soft materials are finding applications in areas ranging from microfluidic device technology
to nanofabrication. We review recent work in these areas, discuss the motivation for device …

The full promise of human genomics will be realized only when the genomes of thousands of
individuals can be sequenced for comparative analysis. A reference sequence enables the …

Soft lithography is an alternative to silicon-based micromachining that uses replica molding
of nontraditional elastomeric materials to fabricate stamps and microfluidic channels. We …

We developed high-density microfluidic chips that contain plumbing networks with thousands
of micromechanical valves and hundreds of individually addressable chambers. These …

We have developed an integrated microfabricated cell sorter using multilayer soft lithography.
This integrated cell sorter is incorporated with various microfluidic functionalities, including …

We describe devices in which optics and fluidics are used synergistically to synthesize novel
functionalities. Fluidic replacement or modification leads to reconfigurable optical systems, …

Molecular characterization of cell types using single-cell transcriptome sequencing is
revolutionizing cell biology and enabling new insights into the physiology of human organs. We …

Spatiotemporal pattern formation occurs in a variety of nonequilibrium physical and chemical
systems. Here we show that a microfluidic device designed to produce reverse micelles …

The metabolism of oxygen, although central to life, produces reactive oxygen species (ROS)
that have been implicated in processes as diverse as cancer, cardiovascular disease and …