User profiles for Stephen Spatz

Stephen Spatz

US National Poultry Research center
Verified email at usda.gov
Cited by 2524

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects

…, W Li, DM Boucher, S Spatz… - Proceedings of the …, 2002 - National Acad Sciences
Erk5 is a mitogen-activated protein kinase, the biological role of which is largely undefined.
Therefore, we deleted the erk5 gene in mice to assess its function in vivo. Inactivation of the …

A prion protein epitope selective for the pathologically misfolded conformation

…, M Papadopoulos, A Haghighat, SJ Spatz… - Nature medicine, 2003 - nature.com
Conformational conversion of proteins in disease is likely to be accompanied by molecular
surface exposure of previously sequestered amino-acid side chains. We found that induction …

ICTV Virus Taxonomy Profile: Herpesviridae 2021

…, PE Pellett, DS Schmid, SJ Spatz… - Journal of General …, 2021 - microbiologyresearch.org
Members of the family Herpesviridae have enveloped, spherical virions with characteristic
complex structures consisting of symmetrical and non-symmetrical components. The linear, …

Horizontal Transmission of Marek's Disease Virus Requires US2, the UL13 Protein Kinase, and gC

KW Jarosinski, NG Margulis, JP Kamil, SJ Spatz… - Journal of …, 2007 - Am Soc Microbiol
Marek's disease virus (MDV) causes a general malaise in chickens that is mostly characterized
by the development of lymphoblastoid tumors in multiple organs. The use of bacterial …

Infectious laryngotracheitis

M García, S Spatz, JS Guy - Diseases of poultry, 2013 - Wiley Online Library
… Maricarmen García, Stephen Spatz, and James S. Guy … shown as open gray boxes and
gray arrows (Stephen Spatz). … Spatz, SJ, JD Volkening, CL Keeler, GF Kutish, SM Riblet, CM …

Newcastle disease virus (NDV) recombinants expressing infectious laryngotracheitis virus (ILTV) glycoproteins gB and gD protect chickens against ILTV and NDV …

W Zhao, S Spatz, Z Zhang, G Wen, M Garcia… - Journal of …, 2014 - Am Soc Microbiol
Infectious laryngotracheitis (ILT) is a highly contagious acute respiratory disease of chickens
caused by infectious laryngotracheitis virus (ILTV). The disease is controlled mainly through …

Comparative full-length sequence analysis of oncogenic and vaccine (Rispens) strains of Marek's disease virus

SJ Spatz, L Petherbridge, Y Zhao… - Journal of General …, 2007 - microbiologyresearch.org
The complete DNA sequence of the Marek's disease virus serotype 1 vaccine strain CVI988
was determined and consists of 178 311 bp with an overall gene organization identical to …

Molecular epidemiology of infectious laryngotracheitis: a review

KR Menendez, M García, S Spatz, NL Tablante - Avian Pathology, 2014 - Taylor & Francis
Infectious laryngotracheitis (ILT) is an economically important respiratory disease of poultry
that affects the poultry industry worldwide. The disease is caused by gallid herpesvirus I (…

A phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America

…, S He, D Kunec, ML Szpara, SJ Spatz… - Evolutionary …, 2017 - Wiley Online Library
Virulence determines the impact a pathogen has on the fitness of its host, yet current understanding
of the evolutionary origins and causes of virulence of many pathogens is surprisingly …

[HTML][HTML] Genomic sequence analysis of the United States infectious laryngotracheitis vaccine strains chicken embryo origin (CEO) and tissue culture origin (TCO)

M García, J Volkening, S Riblet, S Spatz - Virology, 2013 - Elsevier
The genomic sequences of low and high passages of the United States infectious laryngotracheitis
(ILT) vaccine strains CEO and TCO were determined using hybrid next generation …