User profiles for Stephen Spellman
 | Stephen SpellmanCenter for International Blood and Marrow Transplant Research Verified email at nmdp.org Cited by 19623 |
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation
…, E Petersdorf, M Setterholm, S Spellman… - Blood, The Journal …, 2007 - ashpublications.org
The relative importance of various human leukocyte antigen (HLA) loci and the resolution
level at which they are matched has not been fully defined for unrelated donor transplantation. …
level at which they are matched has not been fully defined for unrelated donor transplantation. …
[HTML][HTML] HLA match likelihoods for hematopoietic stem-cell grafts in the US registry
…, E Williams, J Freeman, S Spellman… - … England Journal of …, 2014 - Mass Medical Soc
Background Hematopoietic stem-cell transplantation (HSCT) is a potentially lifesaving therapy
for several blood cancers and other diseases. For patients without a suitable related HLA-…
for several blood cancers and other diseases. For patients without a suitable related HLA-…
[HTML][HTML] Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation
…, PV Grauman, ZH Hu, SR Spellman… - … England Journal of …, 2017 - Mass Medical Soc
Background Genetic mutations drive the pathogenesis of the myelodysplastic syndrome (MDS)
and are closely associated with clinical phenotype. Therefore, genetic mutations may …
and are closely associated with clinical phenotype. Therefore, genetic mutations may …
Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia
…, SGE Marsh, D Geraghty, S Spellman… - Blood, The Journal …, 2010 - ashpublications.org
Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system.
Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-…
Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-…
Reperfusion injury after focal cerebral ischemia: the role of inflammation and the therapeutic horizon
RECENT EVIDENCE INDICATES that thrombolysis may be an effective therapy for the treatment
of acute ischemic stroke. However, the reperfusion of ischemic brain comes with a price…
of acute ischemic stroke. However, the reperfusion of ischemic brain comes with a price…
[HTML][HTML] A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain
asymptomatic 1 , 2 , 3 – 4 . Although most global efforts have focused on severe illness in …
asymptomatic 1 , 2 , 3 – 4 . Although most global efforts have focused on severe illness in …
[HTML][HTML] HLA-C–Dependent Prevention of Leukemia Relapse by Donor Activating KIR2DS1
…, TA Gooley, JH Chewning, S Spellman… - … England Journal of …, 2012 - Mass Medical Soc
Background Of the cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT),
acute myeloid leukemia (AML) is most sensitive to natural killer (NK)–cell reactivity. …
acute myeloid leukemia (AML) is most sensitive to natural killer (NK)–cell reactivity. …
[HTML][HTML] Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant …
S Arai, M Arora, T Wang, SR Spellman, W He… - Biology of Blood and …, 2015 - Elsevier
Although transplant practices have changed over the last decades, no information is available
on trends in incidence and outcome of chronic graft-versus-host disease (cGVHD) over …
on trends in incidence and outcome of chronic graft-versus-host disease (cGVHD) over …
[HTML][HTML] Current use of and trends in hematopoietic cell transplantation in the United States
Hematopoietic cell transplantation (HCT) is a well-established treatment to control and/or
cure many malignant and nonmalignant diseases involving the hematopoietic system and …
cure many malignant and nonmalignant diseases involving the hematopoietic system and …
Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study
…, M Oudshoorn, O Ringden, S Spellman… - The lancet …, 2012 - thelancet.com
Background The risks after unrelated-donor haemopoietic-cell transplantation with matched
HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 alleles between donor and recipient (10/10 …
HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 alleles between donor and recipient (10/10 …