User profiles for Stephen V. Gordon
Stephen V. GordonUniversity College Dublin, Ireland Verified email at ucd.ie Cited by 27216 |
A new evolutionary scenario for the Mycobacterium tuberculosis complex
The distribution of 20 variable regions resulting from insertion-deletion events in the
genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium …
genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium …
The complete genome sequence of Mycobacterium bovis
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species
and man, with worldwide annual losses to agriculture of $3 billion. The human burden of …
and man, with worldwide annual losses to agriculture of $3 billion. The human burden of …
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays
Whole‐genome comparisons of the tubercle bacilli were undertaken using ordered bacterial
artificial chromosome (BAC) libraries of Mycobacterium tuberculosis and the vaccine strain, …
artificial chromosome (BAC) libraries of Mycobacterium tuberculosis and the vaccine strain, …
Genome plasticity of BCG and impact on vaccine efficacy
To understand the evolution, attenuation, and variable protective efficacy of bacillus
Calmette–Guérin (BCG) vaccines, Mycobacterium bovis BCG Pasteur 1173P2 has been subjected …
Calmette–Guérin (BCG) vaccines, Mycobacterium bovis BCG Pasteur 1173P2 has been subjected …
Bottlenecks and broomsticks: the molecular evolution of Mycobacterium bovis
NH Smith, SV Gordon… - Nature Reviews …, 2006 - nature.com
Mycobacterium bovis is the cause of tuberculosis in cattle and is a member of the Mycobacterium
tuberculosis complex. In contrast to many other pathogenic bacterial species, there is …
tuberculosis complex. In contrast to many other pathogenic bacterial species, there is …
[HTML][HTML] Conclusive evidence that the major t-cell antigens of themycobacterium tuberculosis complex esat-6 and cfp-10 form a tight, 1: 1 complex and characterization …
The proteins ESAT-6 and CFP-10 have been shown to be secreted by Mycobacterium
tuberculosis and Mycobacterium bovis cells, to be potent T-cell antigens, and to have a clear but …
tuberculosis and Mycobacterium bovis cells, to be potent T-cell antigens, and to have a clear but …
Structure and function of the complex formed by the tuberculosis virulence factors CFP‐10 and ESAT‐6
…, FW Muskett, G Kelly, TA Frenkiel, SV Gordon… - The EMBO …, 2005 - embopress.org
The secreted Mycobacterium tuberculosis complex proteins CFP‐10 and ESAT‐6 have recently
been shown to play an essential role in tuberculosis pathogenesis. We have determined …
been shown to play an essential role in tuberculosis pathogenesis. We have determined …
Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis
Much effort has been spent trying to work out the origin and history of tuberculosis. Understanding
these concepts could have important consequences for the development of vaccines …
these concepts could have important consequences for the development of vaccines …
[HTML][HTML] Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia
…, L Yamuah, G Hewinson, SV Gordon… - Emerging infectious …, 2013 - ncbi.nlm.nih.gov
Molecular typing of 964 specimens from patients in Ethiopia with lymph node or pulmonary
tuberculosis showed a similar distribution of Mycobacterium tuberculosis strains between the …
tuberculosis showed a similar distribution of Mycobacterium tuberculosis strains between the …
Ecotypes of the Mycobacterium tuberculosis complex
…, J Inwald, J Dale, JR Driscoll, SV Gordon… - Journal of theoretical …, 2006 - Elsevier
A phylogeny of the Mycobacterium tuberculosis complex has recently shown that the animal-adapted
strains are found in a single lineage marked by the deletion of chromosomal region …
strains are found in a single lineage marked by the deletion of chromosomal region …