Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind …
…, P Celano, K Behbakht, S Davidson, S Welch… - The lancet …, 2017 - thelancet.com
Background Olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, has previously shown
efficacy in a phase 2 study when given in capsule formulation to all-comer patients with …
efficacy in a phase 2 study when given in capsule formulation to all-comer patients with …
[HTML][HTML] Pembrolizumab plus chemotherapy in advanced endometrial cancer
…, EK Hill, PH Thaker, VS John, S Welch… - … England Journal of …, 2023 - Mass Medical Soc
Background Standard first-line chemotherapy for endometrial cancer is paclitaxel plus
carboplatin. The benefit of adding pembrolizumab to chemotherapy remains unclear. Methods In …
carboplatin. The benefit of adding pembrolizumab to chemotherapy remains unclear. Methods In …
[HTML][HTML] The iPlant collaborative: cyberinfrastructure for plant biology
The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF)
funded project that aims to create an innovative, comprehensive, and foundational …
funded project that aims to create an innovative, comprehensive, and foundational …
Olaparib tablets as maintenance therapy in patients with platinum-sensitive relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a final analysis …
…, P Celano, K Behbakht, S Davidson, S Welch… - The Lancet …, 2021 - thelancet.com
Background Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has previously
been shown to extend progression-free survival versus placebo when given to patients with …
been shown to extend progression-free survival versus placebo when given to patients with …
Models for navigating biological complexity in breeding improved crop plants
Progress in breeding higher-yielding crop plants would be greatly accelerated if the
phenotypic consequences of making changes to the genetic makeup of an organism could be …
phenotypic consequences of making changes to the genetic makeup of an organism could be …
Effects of genetic perturbation on seasonal life history plasticity
Like many species, the model plant Arabidopsis thaliana exhibits multiple different life
histories in natural environments. We grew mutants impaired in different signaling pathways in …
histories in natural environments. We grew mutants impaired in different signaling pathways in …
Five-year outcomes of FOLFIRINOX vs gemcitabine as adjuvant therapy for pancreatic cancer: a randomized clinical trial
…, F Aubin, F Couture, E Mc Whirter, S Welch… - JAMA …, 2022 - jamanetwork.com
Importance Early results at 3 years from the PRODIGE 24/Canadian Cancer Trials Group
PA6 randomized clinical trial showed survival benefits with adjuvant treatment with modified …
PA6 randomized clinical trial showed survival benefits with adjuvant treatment with modified …
[BOOK][B] The concept of political culture
S Welch - 2016 - books.google.com
'... erudite, thought-provoking and well-written.'Archie Brown, Professor of Politics, Oxford
University. The return to prominence of the concept of political culture offers an opportunity to re…
University. The return to prominence of the concept of political culture offers an opportunity to re…
[HTML][HTML] Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)
…, DM O'Malley, A Leary, D Provencher, S Welch… - Nature …, 2021 - nature.com
ARIEL2 (NCT01891344) is a single-arm, open-label phase 2 study of the PARP inhibitor (PARPi)
rucaparib in relapsed high-grade ovarian carcinoma. In this post hoc exploratory …
rucaparib in relapsed high-grade ovarian carcinoma. In this post hoc exploratory …
Tapping unsustainable groundwater stores for agricultural production in the High Plains Aquifer of Kansas, projections to 2110
…, X Yang, SA Staggenborg, SM Welch… - Proceedings of the …, 2013 - National Acad Sciences
Groundwater provides a reliable tap to sustain agricultural production, yet persistent aquifer
depletion threatens future sustainability. The High Plains Aquifer supplies 30% of the nation’…
depletion threatens future sustainability. The High Plains Aquifer supplies 30% of the nation’…